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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Investigation of Pupillary Changes After Carotid Endarterectomy and Carotid Stent Placement Using Automated Pupillometry
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Investigation of Pupillary Changes After Carotid Endarterectomy and Carotid Stent Placement Using Automated Pupillometry

机译：用自动瞳孔测定颈动脉内切除术和颈动脉支架术后瞳孔变化研究

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Introduction: Horner's syndrome has been reported after carotid artery endarterectomy (CEA) and carotid artery stenting (CS). This study evaluates pupillary changes after these procedures using automated pupillometry. Methods: Retrospective analysis from a prospective database of pupillometry readings. Cases (14 patients with CEA/CS) were matched to controls (14 patients without CEA/CS). t test models were constructed to examine pupillary light reflex measures for CEA, CS, and controls. Results: The 28 subjects had a mean age of 70 years, 50% were male, and 96% were Caucasian. There was no significant difference in the mean pupil size, constriction velocity (CV), dilation velocity (DV) between the procedural side compared to the contralateral side. However, the mean DV in the left eye after a left sided procedure among CS patients (.67) was lower than mean DV in left eye among controls (.88; P < .0001) and patients undergoing CEA (1.03; P < .0001). Discussion: CS may result in disruption of the carotid artery plexus and decreased sympathetic response thereby reducing DV in the ipsilateral pupil. In addition, decreased CV can also been seen. Conclusion: The findings confirm and extend those of previous authors suggesting that pupillary changes may be seen after CS and automated handheld pupillometry may aid in the detection of Horner Syndrome.
机译：导言：颈动脉内膜切除术（CEA）和颈动脉支架置入术（CS）后出现霍纳综合征。本研究使用自动瞳孔测量法评估这些手术后的瞳孔变化。方法：对一个前瞻性的瞳孔测量数据数据库进行回顾性分析。病例（14例CEA/CS患者）与对照组（14例无CEA/CS患者）匹配。构建t检验模型，检查CEA、CS和对照组的瞳孔光反射测量。结果：28名受试者的平均年龄为70岁，50%为男性，96%为白种人。与对侧相比，手术侧的平均瞳孔大小、收缩速度（CV）、扩张速度（DV）无显著差异。然而，CS患者左侧手术后左眼的平均DV（.67）低于对照组（.88；P<0.0001）和接受CEA患者（1.03；P<0.0001）的左眼平均DV。讨论：CS可能导致颈动脉丛中断，交感神经反应降低，从而减少同侧瞳孔的DV。此外，还可以看到CV降低。结论：这些发现证实并扩展了先前作者的观点，即CS术后可能会出现瞳孔变化，自动手持式瞳孔测量仪可能有助于霍纳综合征的检测。

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