• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Mechanism of Stroke According to the Severity and Location of Atherosclerotic Middle Cerebral Artery Disease
【24h】

Mechanism of Stroke According to the Severity and Location of Atherosclerotic Middle Cerebral Artery Disease

机译：卒中机制根据动脉粥样硬化中动脉疾病的严重程度和位置

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and purpose: Strategy for secondary prevention of ischemic stroke depends on the mechanism of stroke. The aim of this study was to compare the stroke mechanism according to the location and severity of middle cerebral artery (MCA) disease. Methods: We analyzed acute ischemic stroke patients within 7 days of onset with symptomatic MCA disease. The location of MCA disease was classified into proximal MCA M1 (pMCA) and distal MCA M1 /proximal M2 (dMCA). The mechanism of stroke was categorized according to the pattern of ischemic lesion: local branch occlusion, artery-to-artery embolism/hemodynamic infarction, in situ-thrombosis, or a combined mechanism. The mechanism and imaging characteristics of stroke were compared according to the location and severity. The factors associated with the stroke mechanism were also investigated. Results: A symptomatic MCA disease was observed in 126 patients (74 pMCA and 52 dMCA). The mechanism of stroke differed according to the location (p < 0.001); the combined mechanism was most common in pMCA disease (54.1%), especially in those who presented with MCA occlusion and with a susceptible vessel sign. Artery-to-artery embolism/hemodynamic infarction was most common in dMCA disease (46.2%). A longer length of stenosis was observed in local branch occlusion than in other mechanisms (p = 0.04) and was an independent factor associated with local branch occlusion (OR=1.631, 95% CI=1.161-2.292; p = 0.005). Conclusions: The mechanism of stroke differed according to the location of MCA disease: occlusion caused by plaque rupture with combined mechanism of stroke type was predominant in pMCA. Longer length of stenosis was associated with local branch occlusion.
机译：背景和目的：缺血性中风的二级预防策略取决于中风的机制。本研究的目的是根据大脑中动脉（MCA）疾病的位置和严重程度，比较中风机制。方法：我们分析了症状性MCA疾病发作7天内的急性缺血性卒中患者。MCA病变的部位分为近端MCA M1（pMCA）和远端MCA M1/近端M2（dMCA）。中风的机制根据缺血性病变的模式进行分类：局部分支闭塞、动脉间栓塞/血流动力学梗死、原位血栓形成或联合机制。根据中风的部位和严重程度，比较其发病机制和影像学特征。与中风机制相关的因素也进行了调查。结果：126例患者（74例pMCA和52例dMCA）出现症状性MCA。卒中机制因部位不同而不同（p<0.001）；这种综合机制在pMCA疾病中最为常见（54.1%），尤其是那些出现MCA闭塞和易感血管征象的患者。动脉间栓塞/血流动力学梗死在dMCA疾病中最常见（46.2%）。与其他机制相比，局部分支闭塞的狭窄长度更长（p=0.04），是与局部分支闭塞相关的独立因素（OR=1.631，95%CI=1.161-2.292；p=0.005）。结论：根据MCA疾病的部位，卒中的机制不同：pMCA中以斑块破裂引起的闭塞和卒中类型的综合机制为主。狭窄长度较长与局部分支闭塞有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号