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首页> 外文期刊>Journal of Veterinary Dentistry >Early Analgesic Efficacy of Morphine, Butorphanol, Lidocaine, Bupivacaine or Carprofen After Periodontal Treatment in Dogs
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Early Analgesic Efficacy of Morphine, Butorphanol, Lidocaine, Bupivacaine or Carprofen After Periodontal Treatment in Dogs

机译：吗啡，丁啡醇，利多卡因，布比卡因或携带术后牙齿治疗后的早期镇痛疗效

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The early effectiveness of 5 analgesics was investigated after periodontal treatment. Dogs were assigned to 6 groups (n = 14 each). A prospective, randomized and blinded clinical study was performed. Before anesthesia was induced, butorphanol, morphine, carprofen and saline were administered. After induction, a maxillary and mandibular block was performed with lidocaine or bupivacaine. Painful periodontal therapies were performed. Two hours after the administration of analgesics and after anesthesia reversal, pain was scored using the Visual Analog Scale for pain (VAS) and the modified University of Melbourne Pain Score (UMPS). Blood glucose and cortisol levels were measured prior to analgesic administration and again 2 hours later. Rescue analgesia was provided when the VAS exceeded 50 mm or the UMPS exceeded 14 points. Rescue analgesia was required in one patient in the morphine group and one in the carprofen group. The VAS values were significantly lower in the butorphanol group compared to those of the saline group and in the bupivacaine group vs. those in the saline and lidocaine groups. Significantly lower UMPS values were obtained in the bupivacaine group compared to those in the saline, butorphanol and lidocaine groups and in the carprofen group vs. those in the saline and lidocaine groups. Significantly higher serum cortisol values were found in the lidocaine group compared to those in the saline, bupivacaine and carprofen groups. Administration of carprofen or the use of nerve blocks with bupivacaine improved analgesia after periodontal treatment more than did butorphanol, morphine or nerve blocks using lidocaine.
机译：在牙周治疗后，对5种止痛药的早期疗效进行了研究。将狗分为6组（每组14只）。进行了一项前瞻性、随机、盲法临床研究。麻醉诱导前，给予布托啡诺、吗啡、卡普洛芬和生理盐水。诱导后，用利多卡因或布比卡因进行上下颌阻滞。进行痛苦的牙周治疗。两个小时后，止痛药和麻醉逆转后，疼痛评分使用视觉模拟量表疼痛（VAS）和修改后的墨尔本大学疼痛评分（UMPS）。在给药前和给药2小时后分别测量血糖和皮质醇水平。当VAS超过50 mm或UMPS超过14分时，给予抢救性镇痛。吗啡组和卡普洛芬组各有一名患者需要进行抢救性镇痛。布托啡诺组的VAS值显著低于生理盐水组，布比卡因组显著低于生理盐水组和利多卡因组。与生理盐水组、布托啡诺组和利多卡因组相比，布比卡因组的UMPS值显著降低；与生理盐水组和利多卡因组相比，卡普洛芬组的UMPS值显著降低。利多卡因组的血清皮质醇值明显高于生理盐水、布比卡因和卡普洛芬组。与布托啡诺、吗啡或利多卡因神经阻滞相比，卡普洛芬或布比卡因神经阻滞对牙周治疗后的镇痛效果更好。

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