首页> 外文期刊>Annals of Tropical Paediatrics >Introduction of rotavirus vaccines in developing countries: remaining challenges.
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Introduction of rotavirus vaccines in developing countries: remaining challenges.

机译:发展中国家引入轮状病毒疫苗:仍然存在的挑战。

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Rotavirus is the principal agent of severe, dehydrating gastro-enteritis in infants and young children worldwide. The main public health tool that can prevent hospitalisation and death from rotavirus is vaccination. One of two current rotavirus vaccines is now licensed in more than 80 countries and is incorporated into childhood immunisation schedules across several countries in the Americas and Europe. However, since the majority of childhood deaths from rotavirus occur in the developing countries of Africa and Asia, widespread use of vaccine in these two continents will be necessary before a major impact on global diarrhoea mortality is seen. Challenges in these latter settings which primarily relate to vaccine efficacy, safety and financing will be addressed within the next 3-5 years, and thus perhaps finally allow introduction of rotavirus vaccine into the populations in greatest need.
机译:轮状病毒是全世界婴幼儿严重脱水胃肠炎的主要病因。预防轮状病毒住院和死亡的主要公共卫生工具是疫苗接种。目前,两种轮状病毒疫苗中的一种已在80多个国家/地区获得许可,并已纳入美洲和欧洲多个国家/地区的儿童免疫计划中。但是,由于轮状病毒在儿童期造成的大多数死亡发生在非洲和亚洲的发展中国家,因此在看到对全球腹泻死亡率的重大影响之前,有必要在这两个大洲广泛使用疫苗。在后面的这些环境中,主要与疫苗效力,安全性和筹资有关的挑战将在未来3-5年内解决,因此也许最终可以将轮状病毒疫苗引入最需要的人群。

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