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首页> 外文期刊>Brain research >Social behaviors and gray matter volumes of brain areas supporting social cognition in children and adolescents with prenatal alcohol exposure
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Social behaviors and gray matter volumes of brain areas supporting social cognition in children and adolescents with prenatal alcohol exposure

机译：支持儿童和青少年的社会认知脑区的社会行为和灰质卷

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The goal of this study was to examine: 1) differences in parent-reported prosocial and antisocial behaviors between children and adolescents with and without prenatal alcohol exposure (PAE); 2) differences in gray matter volumes of brain areas supporting social cognition between children and adolescents with and without PAE; 3) correlations between gray matter volumes of brain areas supporting social cognition and parent-reported prosocial and antisocial behaviors. Parents of children and adolescents ages 8-16 years completed measures on their prosocial and antisocial behaviors (i.e., Behavior Assessment Scale for Children, Vineland Adaptive Behaviors Scales, and Child Behavior Checklist) (n = 84; 41 with PAE, 43 without PAE). Seventy-nine participants (40 with PAE, 39 without PAE) also completed a structural Magnetic Resonance Imaging (MRI) scan with quality data. Gray matter volumes of seven brain areas supporting social cognitive processes were computed using automated procedures (FreeSurfer 6.0): bilateral fusiform gyrus, superior temporal gyrus, medial orbitofrontal cortex, lateral orbitofrontal cortex, posterior cingulate cortex, precuneus, and temporal pole.
机译：本研究的目的是检验：1）有无产前酒精暴露（PAE）的儿童和青少年在父母报告的亲社会和反社会行为方面的差异；2） 有PAE和无PAE的儿童和青少年支持社会认知的脑区灰质体积的差异；3） 支持社会认知的大脑区域灰质体积与父母报告的亲社会和反社会行为之间的相关性。8-16岁儿童和青少年的父母完成了亲社会和反社会行为的测量（即儿童行为评估量表、Vineland适应行为量表和儿童行为检查表）（n=84；41例PAE，43例无PAE）。79名参与者（40名患有PAE，39名没有PAE）也完成了结构磁共振成像（MRI）扫描，获得了高质量的数据。使用自动化程序（FreeSurfer 6.0）计算支持社会认知过程的七个大脑区域的灰质体积：双侧梭状回、颞上回、内侧眶额皮质、外侧眶额皮质、后扣带回皮质、楔前叶和颞极。

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