Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

著录项

• 来源
  《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2021年第1期|共16页
• 作者

  Ren Chaowei; Sun Ning; Kong Ying; Qu Xiaojuan; Liu Haixia; Zhong Hui; Song Xiaoling; Yang Xiaobao; Jiang Biao;

  展开▼
• 作者单位

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  Jing Med Technol Shanghai Ltd Y Bldg 230 Haike Rd Shanghai 201210 Peoples R China;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  ShanghaiTech Univ Shanghai Inst Adv Immunochem Studies 393 Middle Huaxia Rd Shanghai 201210;

  展开▼
• 收录信息
• 原文格式 PDF
• 正文语种 eng
• 中图分类 药学;
• 关键词

  Anaplastic lymphoma kinase; Proteolysis targeting chimeras; Alectinib; CRBN; Anaplastic large-cell lymphomas; Oral bioavailability;