Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

Prasad Saumya; Chandra Anil; Cavo Marta; Parasido Erika; Fricke Stanley; Lee Yichien; DAmone Eliana; Gigli Giuseppe; Albanese Chris; Rodriguez Olga; del Mercato Loretta L.

首页> 外文期刊>Nanotechnology >Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

【24h】

Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

机译：用于研究肿瘤微环境的光学和磁共振成像方法：最先进的审查和未来趋势

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two of the most characterized properties of the TME are acidosis and hypoxia, both of which are considered hallmarks of tumours as well as critical factors in response to anticancer treatments. Currently, various imaging approaches exist to measure acidosis and hypoxia in the TME, including magnetic resonance imaging (MRI), positron emission tomography and optical imaging. In this review, we will focus on the latest fluorescent-based methods for optical sensing of cell metabolism and MRI as diagnostic imaging tools applied both in vitro and in vivo. The primary emphasis will be on describing the current and future uses of systems that can measure intra- and extra-cellular pH and oxygen changes at high spatial and temporal resolution. In addition, the suitability of these approaches for mapping tumour heterogeneity, and assessing response or failure to therapeutics will also be covered.

机译：肿瘤微环境（TME）强烈影响肿瘤的发生和转移。TME最具特征的两个特性是酸中毒和缺氧，这两个特性都被认为是肿瘤的特征，也是对抗癌治疗做出反应的关键因素。目前，有各种成像方法可以测量TME中的酸中毒和缺氧，包括磁共振成像（MRI）、正电子发射断层成像和光学成像。在这篇综述中，我们将重点介绍最新的基于荧光的细胞代谢光学传感方法和MRI作为诊断成像工具在体外和体内的应用。主要重点将是描述能够以高时空分辨率测量细胞内和细胞外pH和氧气变化的系统的当前和未来用途。此外，还将介绍这些方法在绘制肿瘤异质性图、评估治疗反应或失败方面的适用性。

著录项

来源
《Nanotechnology》 |2021年第6期|共36页
作者
Prasad Saumya; Chandra Anil; Cavo Marta; Parasido Erika; Fricke Stanley; Lee Yichien; DAmone Eliana; Gigli Giuseppe; Albanese Chris; Rodriguez Olga; del Mercato Loretta L.;
展开▼
作者单位

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

Georgetown Univ Med Ctr Dept Oncol Washington DC 20007 USA;

Georgetown Univ Med Ctr Dept Oncol Washington DC 20007 USA;

Georgetown Univ Med Ctr Dept Oncol Washington DC 20007 USA;

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

Georgetown Univ Med Ctr Dept Oncol Washington DC 20007 USA;

Georgetown Univ Med Ctr Dept Oncol Washington DC 20007 USA;

CNR Natl Res Council NANOTEC Inst Nanotechnol C-O Campus Ecotekne Via Monteroni I-73100 Lecce Italy;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类特种结构材料;
关键词
fluorescence microscopy; magnetic resonance imaging; tumor micorenvironment; optical sensing;

机译：荧光显微镜;磁共振成像;肿瘤微环境;光学传感;

相似文献

外文文献
中文文献
专利

1. Targeted nanoparticles for the non-invasive detection of traumatic brain injury by optical imaging and fluorine magnetic resonance imaging [J] . Luis Javier Cruz1, Ivo Que1, Markus Aswendt2, 纳米研究：英文版 . 2016,第005期
2. Targeted nanoparticles for the non-invasive detection of traumatic brain injury by optical imaging and fluorine magnetic resonance imaging [J] . Luis Javier Cruz, Ivo Que, Markus Aswendt, 纳米研究（英文版） . 2016,第005期
3. The utility of routine surveillance screening with magnetic resonance imaging (MRI) to detect tumour recurrence in children with low-grade central nervous system (CNS) tumours: a systematic review [J] . Stevens Simon P., Main Caroline, Bailey Simon, Journal of neuro-oncology. . 2018,第3期

机译：常规监测筛查用磁共振成像（MRI）的效用，以检测低级中枢神经系统（CNS）肿瘤的儿童肿瘤复发：系统审查
4. The impact of routine surveillance screening with magnetic resonance imaging (MRI) to detect tumour recurrence in children with central nervous system (CNS) tumours: protocol for a systematic review and meta-analysis [J] . Caroline Main, Simon P. Stevens, Simon Bailey, Systematic Reviews . 2016,第1期

机译：常规监视筛查与磁共振成像（MRI）检测对中枢神经系统（CNS）肿瘤患儿肿瘤复发的影响：系统评价和荟萃分析的方案
5. Modified Genetic Algorithm approaches for classification of abnormal Magnetic Resonance Brain tumour images [J] . Hemanth D. Jude, Anitha J. Applied Soft Computing . 2019,第期

机译：异常磁共振脑肿瘤图像分类的修改遗传算法方法
6. Current and Future Trends in Magnetic Resonance Imaging (MRI) [C] . J. Thomas Vaughan, Carl Snyder, Lance DelaBarre, IEEE MTT-S International Microwave Symposium . 2006

机译：磁共振成像的当前和未来趋势（MRI）
7. Complimentary Approaches to Sensitivity Enhancement in Magnetic Resonance Imaging: Active Feedback Enhanced Imaging and Magnetic Resonance-Functionalized Supramolecular Nanoparticles. [D] . Wolahan, Stephanie M. 2011

机译：磁共振成像中增强感光度的补充方法：主动反馈增强成像和磁共振功能超分子纳米粒子。
8. A State-of-the-Art Review for Gastric Histopathology Image Analysis Approaches and Future Development [O] . Shiliang Ai, Chen Li, Xiaoyan Li, 2021

机译：胃组织病理学图像分析方法和未来发展的最先进的评论
9. Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends [O] . Saumya Prasad, Anil Chandra, Marta Cavo, 2020

机译：用于研究肿瘤微环境的光学和磁共振成像方法：最先进的审查和未来趋势
10. Magnetic Resonance Spectroscopy Imaging and Function Magnetic Resonance Imaging of Neurofibromatosis Type I: In vivo Pathophysiology, Brain-Behavior Relationships and Reading Disabilities [R] . Cutting, L. E. 2005

机译：神经纤维瘤病的磁共振波谱成像和功能磁共振成像I型：体内病理生理学，脑行为关系和阅读障碍

Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends

摘要

著录项

相似文献

相关主题

期刊订阅