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首页> 外文期刊>Optics Letters >Photoacoustic-fluorescence microendoscopy in vivo
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Photoacoustic-fluorescence microendoscopy in vivo

机译：体内光声荧光微观镜检查

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摘要

A miniature endoscope capable of imaging multiple tissue contrasts in high resolution is highly attractive, because it can provide complementary and detailed tissue information of internal organs. Here we present a photoacoustic (PA)-fluorescence (FL) endoscope for optical-resolution PA microscopy (PAM) and FL microscopy (FLM). The endoscope with a diameter of 2.8 mm achieves high lateral resolutions of 5.5 and 6.3 mu m for PAM and FLM modes, respectively. In vivo imaging of zebrafish larvae and a mouse ear is conducted, and high-quality images are obtained. Additionally, in vivo endoscopic imaging of a rat rectum is demonstrated, showing the endoscopic imaging capability of our endoscope. By providing dual contrasts with high resolution, the endoscope may open up new opportunities for clinical endoscopic imaging applications. (C) 2021 Optical Society of America
机译：能够以高分辨率成像多个组织对比度的微型内窥镜极具吸引力，因为它可以提供内部器官的补充和详细组织信息。在这里，我们介绍了一种用于光学分辨率PA显微镜（PAM）和FL显微镜（FLM）的光声（PA）-荧光（FL）内窥镜。直径为2.8mm的内窥镜在PAM和FLM模式下的横向分辨率分别为5.5和6.3μm。对斑马鱼幼虫和小鼠耳朵进行活体成像，获得高质量图像。此外，还展示了大鼠直肠的活体内窥镜成像，显示了我们的内窥镜的内窥镜成像能力。通过提供高分辨率的双重对比，内窥镜可能为临床内窥镜成像应用开辟新的机会。（2021）美国光学学会

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  • 来源
    《Optics Letters》 |2021年第10期|共4页
  • 作者

    Yang Wenzhao; Zhou Jiasheng; Shao Weihao; Seong Myeongsu; He Pengbo; Ye Zhanhong; Guo Zhendong; Jing Lili; Chen Sung-Liang;

  • 作者单位

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Sch Pharm Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Sch Pharm Shanghai 200240 Peoples R China;

    Shanghai Jiao Tong Univ Univ Michigan Shanghai Jiao Tong Univ Joint Inst Shanghai 200240 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 计量学;光学;
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