SpyGlass-guided laser lithotripsy versus laparoscopic common bile duct exploration for large common bile duct stones: a non-inferiority trial

Li Guodong; Pang Qiuping; Zhai Hailan; Zhang Xiujuan; Dong Yanchun; Li Ji; Jia Xinyong

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SpyGlass-guided laser lithotripsy versus laparoscopic common bile duct exploration for large common bile duct stones: a non-inferiority trial

机译：对大型胆总管石头的腹腔镜普通胆管探索的幼眼引导激光碎石术：非卑鄙试验

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Background Laparoscopic common bile duct exploration (LCBDE) is the first choice of treatment for large common bile duct (CBD) stones. Recently, single-operator cholangioscopy (SpyGlass system) has been introduced widely in referral and large medical centers. Several studies have reported favorable results for treatment of large CBD stones guided by SpyGlass. We evaluated the clinical efficacy and safety of SpyGlass-guided laser lithotripsy LCBDE for treatment of large CBD stones. Methods From August 2015 to August 2018, 157 patients with large bile duct stones who met the inclusion criteria were randomly divided into two groups: SpyGlass-guided laser lithotripsy (Group A) and LCBDE (Group B). The efficacy and complications were compared between the groups. Results Although the first-session stone removal rate in Group A was significantly lower than that in Group B, Group A was not inferior to Group B in terms of total stone removal rate. Compared with Group B, Group A had shorter hospital stay and enhanced recovery. The short-term complication rates were also similar between the two groups. Conclusions The clinical efficacy of SpyGlass-guided laser lithotripsy for the treatment of large CBD stones is not inferior to that of LCBDE, and it is less invasive. SpyGlass-guided laser lithotripsy is an important option for treatment of large CBD stones.

机译：背景腹腔镜胆总管探查术（LCBDE）是治疗大型胆总管结石的首选方法。最近，单操作员胆道镜（SpyGlass系统）在转诊和大型医疗中心得到了广泛应用。几项研究报告了在望远镜引导下治疗大型CBD结石的良好结果。我们评估了窥镜引导激光碎石术治疗大型胆总管结石的临床疗效和安全性。方法2015年8月至2018年8月，将157例符合纳入标准的大胆管结石患者随机分为两组：窥镜引导激光碎石术（A组）和LCBDE（B组）。比较两组的疗效和并发症。结果A组第一次取石率明显低于B组，但总取石率并不低于B组。与B组相比，A组住院时间短，恢复快。两组的短期并发症发生率也相似。结论窥镜引导下激光碎石术治疗巨大胆总管结石的临床疗效不低于LCBDE，且创伤小。望远镜引导激光碎石术是治疗大型胆总管结石的重要方法。

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来源
《Surgical Endoscopy》 |2021年第7期|共9页
作者
Li Guodong; Pang Qiuping; Zhai Hailan; Zhang Xiujuan; Dong Yanchun; Li Ji; Jia Xinyong;
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Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Hepatobiliary Surg Jinan 250014 Peoples R China;

Shandong First Med Univ Affiliated Hosp 1 Dept Endoscopy Jinan 250014 Peoples R China;

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正文语种 eng
中图分类诊断学;
关键词
Common bile duct stones; Laser lithotripsy; Laparoscopy; Common bile duct exploration;

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SpyGlass-guided laser lithotripsy versus laparoscopic common bile duct exploration for large common bile duct stones: a non-inferiority trial

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