• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annual Review of Analytical Chemistry >Microfluidics Using Spatially Defined Arrays of Droplets in One, Two, and Three Dimensions
【24h】

Microfluidics Using Spatially Defined Arrays of Droplets in One, Two, and Three Dimensions

机译：使用一维，二维和三维空间定义的液滴阵列的微流控

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Spatially defined arrays of droplets differ from bulk emulsions in that droplets in arrays can be indexed on the basis of one or more spatial variables to enable identification, monitoring, and addressability of individual droplets. Spatial indexing is critical in experiments with hundreds to millions of unique compartmentalized microscale processes--for example, in applications such as digital measurements of rare events in a large sample, high-throughput time-lapse studies of the contents of individual droplets, and controlled droplet-droplet interactions. This review describes approaches for spatially organizing and manipulating droplets in one-, two-, and three-dimensional structured arrays, including aspiration, laminar flow, droplet traps, the SlipChip, self-assembly, and optical or electrical fields. This review also presents techniques to analyze droplets in arrays and applications of spatially defined arrays, including time-lapse studies of chemical, enzymatic, and cellular processes, as well as further opportunities in chemical, biological, and engineering sciences, including perturbation/response experiments and personal and point-of-care diagnostics.
机译：液滴的空间定义阵列与散装乳液的不同之处在于，可以基于一个或多个空间变量对阵列中的液滴进行索引，以实现对单个液滴的识别，监视和寻址。空间索引对于使用数百至数百万个独特的分隔微过程进行的实验至关重要-例如，在诸如对大型样品中的稀有事件进行数字测量，对单个液滴的含量进行高通量时移研究以及受控等应用中小滴-小滴相互作用。这篇综述描述了在空间上组织和操纵一维，二维和三维结构化阵列中的液滴的方法，包括抽吸，层流，液滴捕集器，滑动芯片，自组装以及光学或电场。这篇综述还提出了分析阵列中的液滴的技术以及空间定义的阵列的应用，包括化学，酶和细胞过程的时移研究，以及化学，生物学和工程科学的更多机会，包括扰动/响应实验以及个人和即时诊断。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号