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首页> 外文期刊>Annals of epidemiology >Cardiovascular disease in patients with chronic obstructive pulmonary disease, Saskatchewan Canada cardiovascular disease in COPD patients.
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Cardiovascular disease in patients with chronic obstructive pulmonary disease, Saskatchewan Canada cardiovascular disease in COPD patients.

机译：慢性阻塞性肺疾病患者的心血管疾病，加拿大萨斯喀彻温省COPD患者的心血管疾病。

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PURPOSE: To measure prevalence, incidence, and mortality of cardiovascular outcomes among persons with chronic obstructive pulmonary disease (COPD) and to assess the extent these outcomes differ from persons without COPD. METHODS: Retrospective cohort study in longitudinal health care databases maintained by the government of Saskatchewan, Canada. Subjects were persons age 40 years or older who were diagnosed with COPD during 1997-2000 and who received two or more prescriptions for bronchodilators within 6 months of diagnosis. Each subject was matched by age and sex to two controls without COPD or asthma. RESULTS: Of COPD patients (n = 11,493), 54% were male, and 74% were 65 years or older. Prevalence of all cardiovascular diseases was higher in the COPD group than in the comparison group. After adjusting for cardiovascular risk, odds ratios of prevalence were: arrhythmia 1.76 (confidence interval [CI]: 1.64-1.89), angina 1.61 (CI: 1.47-1.76), acute myocardial infarction 1.61 (CI: 1.43-1.81), congestive heart failure 3.84(CI: 3.56-4.14), stroke 1.11 (CI: 1.02-1.21), pulmonary embolism 5.46 (CI: 4.25-7.02). Risk of hospitalization due to each cardiovascular cause was elevated in the COPD group. The risk ratio for cardiovascular mortality was 2.07 (CI: 1.82-2.36) and all cause mortality was 2.82 (CI: 2.61-3.05). CONCLUSIONS: Persons with diagnosed and treated COPD are at increased risk for hospitalizations and deaths due to cardiovascular diseases.
机译：目的：测量慢性阻塞性肺疾病（COPD）患者的心血管结局患病率，发生率和死亡率，并评估这些结局与无COPD患者的差异。方法：在加拿大萨斯喀彻温省政府维护的纵向卫生保健数据库中进行回顾性队列研究。对象是年龄在40岁以上的人，在1997-2000年期间被诊断出患有COPD，并且在诊断后的6个月内接受了两种或多种支气管扩张药的处方。每个受试者的年龄和性别均与两个没有COPD或哮喘的对照组匹配。结果：在COPD患者（n = 11,493）中，男性占54％，年龄在65岁以上的占74％。 COPD组的所有心血管疾病患病率均高于对照组。调整心血管风险后，患病率的几率是：心律失常1.76（可信区间[CI]：1.64-1.89），心绞痛1.61（CI：1.47-1.76），急性心肌梗塞1.61（CI：1.43-1.81），充血性心脏失败3.84（CI：3.56-4.14），中风1.11（CI：1.02-1.21），肺栓塞5.46（CI：4.25-7.02）。 COPD组由于各种心血管原因而住院的风险增加。心血管死亡的风险比为2.07（CI：1.82-2.36），所有原因的死亡率为2.82（CI：2.61-3.05）。结论：患有COPD并已接受治疗的人因心血管疾病而住院和死亡的风险增加。

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