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首页> 外文期刊>Annals of epidemiology >Period and birth-cohort effects on age of first phencyclidine (PCP) use among drug users in New York City, 1960 to 2000.
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Period and birth-cohort effects on age of first phencyclidine (PCP) use among drug users in New York City, 1960 to 2000.

机译:纽约市1960年至2000年吸毒者首次使用苯环利定(PCP)的年龄和出生队列的影响。

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PURPOSE: The aim of the study is to determine period and birth-cohort effects in the early initiation of phencyclidine (PCP) use in drug users in New York City (NYC). METHODS: We analyzed data collected from two surveys of street-recruited drug users in NYC. We used survival analysis and proportional hazards modeling to assess period and birth-cohort effects on risk for early initiation of PCP use. RESULTS: Of 787 participants, 292 (37.1%) had used PCP by the age of 23 years. Before 1987, there was a greater risk for initiation of PCP use through the age of 23 years (hazard ratio [HR] = 34.77; 95% confidence interval [CI], 21.45-56.36). Proportional hazards modeling showed that those born in the 1971 to 1975 birth cohort compared with those born in 1976 to 1980 had a lower risk for initiation of PCP use through age 23 years (HR = 0.58; 95% CI, 0.37-0.91). Other significant predictors of PCP use by age 23 included white race and having been in a juvenile detention center. CONCLUSIONS: There are period and birth-cohort differences in the likelihood of early initiation of PCP use. Changes in drug culture and social norms may influence the likelihood of initiation of PCP use. This may have implications for interventions aimed at slowing the nationwide increase in use of PCP.
机译:目的:本研究的目的是确定纽约市(NYC)吸毒者早期使用苯环利定(PCP)的时期和出生队列的影响。方法:我们分析了从两次纽约市街头招募吸毒者调查中收集的数据。我们使用了生存分析和比例风险模型来评估时期和出生队列对PCP早期使用风险的影响。结果:在787名参与者中,有292名(37.1%)在23岁之前使用了PCP。 1987年之前,在23岁之前开始使用PCP的风险更大(危险比[HR] = 34.77; 95%置信区间[CI],21.45-56.36)。比例风险模型显示,与1976年至1980年出生的人群相比,1971年至1975年出生的人群在23岁之前开始使用PCP的风险较低(HR = 0.58; 95%CI,0.37-0.91)。到23岁时使用PCP的其他重要预测指标包括白人种族和曾在少年拘留所中。结论:早期开始使用PCP的可能性存在时期和出生队列的差异。毒品文化和社会规范的变化可能会影响开始使用五氯苯酚的可能性。这可能对旨在减缓全国范围内五氯苯酚使用量增长的干预措施有影响。

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