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Magnetic Nanoparticles with Cyclodextrin for Targeted Drug Delivery

机译：磁性纳米颗粒含有靶向药物的环糊精

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The major disadvantage of most chemotherapeutic approaches to cancer treatment is that most of them are non-specific. These non-specific techniques result in the well-known side effects of chemotherapy as the cytotoxic drug attacks normal, healthy cells in addition to its primary target, tumor cells. To overcome this great disadvantage, targeted drug delivery systems such as magnetic nanoparticles can be used [1]. Magnetic nanoparticles are a class of nanoparticles which can be manipulated using magnetic field. These particles have been widely studied because of their potential applications in biomedicines such as tags in sensing and imaging, as active agents in hyperthermia therapy [2], in biomolecular separation, targeted drug delivery, cancer diagnosis and treatment, DNA separation and detection, sequencing of oligonucleotides, magnetic resonance imaging, etc. Among magnetic particles, iron oxides (Fe2O3 and Fe3O4) and other iron salts like chloride, sulfate, etc. have been extensively investigated [3].
机译：大多数化学治疗方法的癌症治疗方法的主要缺点是，其中大多数是非特异性的。这些非特异性技术导致化学疗法众所周知的副作用，因为细胞毒性药物攻击正常的健康细胞外，除了其主要靶标肿瘤细胞外。为了克服这一巨大的缺点，可以使用靶向药物输送系统（例如磁性纳米颗粒）[1]。磁性纳米颗粒是一类纳米颗粒，可以使用磁场进行操纵。这些颗粒在生物医学中的潜在应用，例如在感应和成像中的标签，作为高温治疗中的活性剂[2]，在生物分子分离，靶向药物递送，癌症诊断和治疗，DNA分离和检测，测序，测序，测序在磁性颗粒，氧化铁（Fe2O3和Fe3O4）和其他铁盐（如氯化物，硫酸盐等）中，寡核苷酸，磁共振成像等的含量已得到广泛研究[3]。

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