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Waist-to-thigh ratio is a predictor of internal organ cancers in humans: Findings from a cohort study

机译:腰大腿比是人类内部器官癌的预测指标:一项队列研究的结果

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Objective: Studies have shown that some specific body measures are associated with the occurrence of cancers. Few studies have demonstrated the relationship with more comprehensive approaches. This study aims to explore body measures and the combinations associated with internal organ cancers. Methods: Three-dimensional anthropometric body surface scanning data collected 10,215 participants from the health examination department in a medical center of Taiwan during 2000-2010. Follow-up was conducted for an average of 8 years, and 244 internal organ cancer cases were identified. Results: An increased risk of internal organ cancers was observed among the subjects with larger waist circumference/smaller thigh circumference, in which waist-to-thigh ratio (WTR) was constructed. Comparing the subjects in the fourth quartile for WTR to the subjects in the first quartile with multiple Cox regression analysis yielded a hazard ratio of 1.842 (95% confidence interval, 1.131~2.999). The association between WTR quartile and internal organ cancers was stronger among male participants, older participants, and participants with chronic conditions. Conclusions: The study has revealed that WTR is the most significant predictor for the occurrence of cancer in Asian populations. Because it is easy to measure and open to modification, WTR may be more useful in clinical and preventive medicine in the future.
机译:目的:研究表明,某些特定的身体措施与癌症的发生有关。很少有研究证明与更全面方法的关系。这项研究的目的是探索身体测量以及与内部器官癌相关的组合。方法:2000年至2010年间,三维人体测量表面扫描数据收集了台湾医学中心健康检查部门的10215名参与者。随访平均8年,确定了244例内部器官癌病例。结果:腰围/大腿围较小的受试者中,腰围与大腿的比例(WTR)较高,因此患上内部器官癌的风险增加。 WTR第四个四分位数的受试者与第一个四分位数的受试者进行了多重Cox回归分析,得出危险比为1.842(95%置信区间为1.131〜2.999)。在男性参与者,老年参与者和患有慢性疾病的参与者中,WTR四分位数与内部器官癌之间的关联性更强。结论:研究表明,WTR是亚洲人群中癌症发生率的最重要预测因子。由于WTR易于测量且易于修改,因此将来在临床和预防医学中可能会更加有用。

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