...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of epidemiology >Diabetes mellitus and risk of all-cause mortality among patients with tuberculosis in the state of Georgia, 2009-2012
【24h】

Diabetes mellitus and risk of all-cause mortality among patients with tuberculosis in the state of Georgia, 2009-2012

机译：2009-2012年佐治亚州结核病患者的糖尿病和全因死亡率的风险

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: To estimate the association between diabetes mellitus (DM) and all-cause mortality during tuberculosis (TB) treatment. Methods: From 2009 to 2012, a retrospective cohort study among reported TB cases in Georgia was conducted. Patients aged 16 years or older were classified by DM and human immunodeficiency virus (HIV) status at the time of TB diagnosis and followed during TB treatment to assess mortality. Hazard ratios were used to estimate the association between DM and death. Results: Among 1325 patients with TB disease, 151 (11.4%) had DM, 147 (11.1%) were HIV-infected, and seven (0.5%) had both DM and HIV. Patients with TB-DM were more likely to have cavitary lung disease compared with those with TB alone (51.0% vs. 34.7%) and those with TB-HIV were more likely to have military/disseminated disease (12.9% vs. 3.4%) and resistance to rifampin or isoniazid (21.8% vs. 9.0%) compared with those without HIV infection (P < .05). In multivariable analysis, DM was not associated with death during TB treatment (hazard ratio, 1.22; 95% confidence interval, 0.70-2.12) or any death (adjusted odds ratio, 1.05; 95% confidence interval, 0.60-1.84). Conclusions: Among TB patients in Georgia, the prevalence of comorbid DM and coinfection with HIV was nearly identical. In adjusted models, TB patients with DM did not have increased risk of all-cause mortality.
机译：目的：评估糖尿病（DM）与结核病（TB）治疗期间全因死亡率之间的关联。方法：2009年至2012年，对佐治亚州报告的结核病病例进行了回顾性队列研究。在结核病诊断时，对16岁或16岁以上的患者按DM和人类免疫缺陷病毒（HIV）状况进行分类，并在结核病治疗期间进行随访以评估死亡率。危险比被用来估计糖尿病和死亡之间的关系。结果：在1325名结核病患者中，有151名（11.4％）患有DM，其中147名（11.1％）被HIV感染，七名（0.5％）患有DM和HIV。与仅结核病患者相比，TB-DM患者更有可能发生空洞性肺疾病（51.0％对34.7％），而TB-HIV患者更容易患有军事/弥漫性疾病（12.9％对3.4％）与未感染HIV的患者相比，对利福平或异烟肼的抗性（21.8％对9.0％）（P <.05）。在多变量分析中，DM与结核病治疗期间的死亡（危险比，1.22; 95％置信区间，0.70-2.12）或任何死亡（校正比值比，1.05; 95％置信区间，0.60-1.84）无关。结论：在佐治亚州的结核病患者中，糖尿病合并症和艾滋病合并感染的患病率几乎相同。在调整后的模型中，患有DM的TB患者的全因死亡率没有增加的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号