首页> 外文期刊>Annals of epidemiology >Associations of Body Mass Index and Anthropometric Indicators of Fat Mass and Fat Free Mass with All-cause Mortality among Women in the First and Second National Health and Nutrition Examination Surveys Follow-up Studies.
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Associations of Body Mass Index and Anthropometric Indicators of Fat Mass and Fat Free Mass with All-cause Mortality among Women in the First and Second National Health and Nutrition Examination Surveys Follow-up Studies.

机译:第一次和第二次全国健康和营养检查调查后续研究中妇女的体重指数和人体测量指标,脂肪量和无脂肪量与全因死亡率的关联。

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PURPOSE: This study tests whether fat mass (FM) and fat free mass (FFM) have opposite associations with mortality in a nationally representative sample of females.METHODS: Data on 13,369 female participants from National Health and Nutrition Examination Surveys (NHANES) I and II (aged 25 to 75 years) were analyzed. Mean follow-up time was 16.1 years. Ninety-seven percent of the participants with 3020 deaths were successfully followed. Subscapular and triceps skinfolds thickness were used as a FM indicator (FMI). Upper arm circumference was used as a FFM indicator (FFMI). Cox regression tested the relationships of BMI, FM and FFM with all-cause mortality adjusting for various socio-demographic variables.RESULTS: BMI had a U-shaped relationship with mortality with a nadir of approximately 27 kg/m(2). When FFMI was added to the model, the relationship between BMI and mortality became more monotonic increasing. FMI showed a significant negative relationship with mortality.CONCLUSIONS: Contrary to expectations, both FFMI and FMI had negative relationships with mortality. These results differ from patterns previously observed in males and may reflect sex differences in fat distribution. Research using superior measures of body fat amount and distribution may resolve these discrepancies.
机译:目的:这项研究测试了在全国范围内具有代表性的女性样本中,脂肪量(FM)和无脂肪量(FFM)是否与死亡率具有相反的关系。方法:来自国家健康和营养检查调查(NHANES)I和13369名女性参与者的数据II(25至75岁)进行了分析。平均随访时间为16.1年。成功追踪了30%的参与者中的百分之九十七。肩cap下和肱三头肌的皮褶厚度用作FM指标(FMI)。上臂周围被用作FFM指标(FFMI)。 Cox回归检验了BMI,FM和FFM与全因死亡率进行了各种社会人口统计学变量调整之间的关系。结果:BMI与死亡率呈U形关系,最低谷约为27 kg / m(2)。当将FFMI添加到模型中时,BMI与死亡率之间的关系变得越来越单调。结论:与预期相反,FFMI和FMI与死亡率呈负相关。这些结果与以前在男性中观察到的模式不同,并且可能反映了脂肪分布中的性别差异。使用出色的人体脂肪含量和分布测量方法进行的研究可以解决这些差异。

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