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首页> 外文期刊>Annals of epidemiology >Place of residence effect on likelihood of surviving prostate cancer.
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Place of residence effect on likelihood of surviving prostate cancer.

机译：居住地对存活前列腺癌的可能性有影响。

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PURPOSE: To examine geographic variation in survival time of men diagnosed with prostate cancer, adjusted for patient and disease characteristics. METHOD: Survival times for a geographically referenced database of 27,189 incident prostate cancer cases (ICD-O-2: C61.9) from Connecticut, 1984-1998, were evaluated using a newly developed extension of the spatial scan statistic for survival data. RESULTS: Statewide, median survival time was 4.6 years following diagnosis. Age-adjusted survival times across most locales around Connecticut did not differ markedly from the statewide pattern, but our analysis revealed 3 zones with noteworthy differences. Analysis of survival times adjusted for age as well as tumor grade and stage produced only two locations with significant results, and further adjustment for racial composition of cases yielded only one location with significant distinct (lower) survival times. Among cases within that place, the likelihood of dying was estimated to be 1.39-times greater than that of cases different from those diagnosed elsewhere around the state (p = 0.009). CONCLUSION: The prognosis for men with prostate cancer may differ, in part, by virtue of where they live when diagnosed. Measuring geographic differences in survival time should facilitate the targeting of clinical and ancillary services to persons at high risk of poor outcomes.
机译：目的：检查根据患者和疾病特征调整的诊断为前列腺癌的男性生存时间的地理差异。方法：使用新开发的空间扫描统计数据扩展生存数据，对来自康涅狄格州1984-1998年的27189例前列腺癌事件案例的地理参考数据库（ICD-O-2：C61.9）的生存时间进行了评估。结果：在全州范围内，诊断后中位生存时间为4.6年。康涅狄格州附近大多数地区的年龄调整生存时间与全州模式没有显着差异，但我们的分析显示3个区域存在显着差异。根据年龄，肿瘤等级和分期调整的生存时间分析仅在两个位置产生了显着的结果，对病例种族组成的进一步调整仅在一个位置具有明显的不同（较低）生存时间。在那个地方的病例中，死亡的可能性估计是与该州其他地方诊断出的病例不同的病例的1.39倍（p = 0.009）。结论：前列腺癌男性的预后可能会有所不同，部分取决于诊断时所居住的地方。测量生存时间的地域差异应有助于将临床和辅助服务的目标人群定位为不良结果风险高的人群。

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