...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of epidemiology >Hypertensive disorders in pregnancy and paternal cardiovascular risk: a population-based study.
【24h】

Hypertensive disorders in pregnancy and paternal cardiovascular risk: a population-based study.

机译：妊娠高血压疾病和父亲心血管疾病的风险：一项基于人群的研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: It has been suggested that paternal genes may contribute to the risk of maternal hypertensive disorders in pregnancy and that genes associated with cardiovascular disease could be involved in the etiology of maternal hypertensive disorders in pregnancy. If these genes are of fetal origin, one would expect that paternal cardiovascular risk factors are associated with the fathering of pregnancies in which the mothers experience hypertensive disorders. Thus, we have studied 14,130 offspring and parents in Norway (1967-1997) to assess whether the fathering of pregnancies complicated by hypertensive disorders in the mother is associated with paternal cardiovascular risk factors. METHODS: In a population-based study of 14,130 family units, data on parental cardiovascular risk factors (blood pressure, body mass index, waist circumference, nonfasting serum lipids and glucose) collected in the Norwegian Hunt Study (1995-1997) were linked to pregnancy data from the Medical Birth Registry of Norway (1967-1997). Multiple linear regression methods were used, and all analyses were adjusted for lifestyle factors likely to be shared by the parents. RESULTS: There was no association between hypertensive disorders in pregnancy and paternal cardiovascular risk factors. CONCLUSIONS: We found no evidence that the fathering of pregnancies complicated by hypertensive disorders in the mother is associated with an unfavorable paternal cardiovascular risk profile.
机译：目的：已经提出，父本基因可能会增加孕产妇高血压疾病的风险，而与心血管疾病相关的基因可能与孕产妇高血压疾病的病因有关。如果这些基因是胎儿来源的，人们可能会认为，父亲的心血管危险因素与怀孕的母亲有关，在这些母亲中，母亲患有高血压疾病。因此，我们在挪威（1967-1997年）研究了14,130个后代及其父母，以评估孕妇并发母亲高血压疾病的父亲是否与父亲的心血管危险因素相关。方法：在一项基于人口的14130个家庭单位的研究中，将挪威狩猎研究（1995-1997）收集的父母心血管危险因素（血压，体重指数，腰围，非空腹血脂和葡萄糖）的数据与挪威医疗出生登记处的怀孕数据（1967-1997年）。使用了多种线性回归方法，并对所有分析针对可能由父母共享的生活方式因素进行了调整。结果：妊娠高血压疾病与父亲心血管危险因素之间没有关联。结论：我们没有发现证据表明怀孕与母亲高血压疾病并发与不良的父亲心血管风险有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号