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首页> 外文期刊>Annals of epidemiology >Association between history of abortion and nonalcoholic fatty liver disease in middle-aged and elderly Chinese women
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Association between history of abortion and nonalcoholic fatty liver disease in middle-aged and elderly Chinese women

机译：中国中老年妇女流产史与非酒精性脂肪肝的关系

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Purpose: To evaluate the possible relationship between self-reported history of abortion and nonalcoholic fatty liver disease (NAFLD) in middle-aged and elderly Chinese women. Methods: A cross-sectional study was performed in 5911 women aged 40 years or older in Jiading District, Shanghai, China. Reproductive histories, including miscarriage and induced abortion, were collected using a validated questionnaire by trained physicians. Abdominal B-mode ultrasound evaluation and serum liver enzymes levels were used in the diagnosis of NAFLD. Results: The percentage reporting history of abortion in women with NAFLD was higher than in those without NAFLD (72.4% vs. 69.3%, age-adjusted P = .001). Compared with women without a history of abortion, the fully adjusted odds ratio (OR) for NAFLD in those with a history of abortion was increased by 28% (OR, 1.28 and 95% confidence interval [CI], 1.06-1.55). Histories of miscarriage and induced abortion were also associated with increased risk of prevalent NAFLD in fully adjusted models (OR, 1.84 and 95% CI, 1.24-2.72; OR, 1.23 and 95% CI, 1.02-1.50, respectively). Conclusions: Both miscarriage and induced abortion are associated with prevalent NAFLD in middle-aged and elderly Chinese women. ? 2013 Elsevier Inc.
机译：目的：评估自我报告的流产史与中老年中国妇女非酒精性脂肪肝疾病（NAFLD）之间的可能关系。方法：在中国上海市嘉定区对5911名40岁以上的女性进行了横断面研究。生殖史，包括流产和人工流产，是由经过培训的医生使用经过验证的问卷收集的。腹部B超检查和血清肝酶水平用于NAFLD的诊断。结果：患有NAFLD的妇女的流产报告历史百分比高于没有NAFLD的妇女（72.4％对69.3％，年龄校正后的P = .001）。与没有流产史的妇女相比，有流产史的妇女的NAFLD完全调整比值比（OR）增加了28％（OR为1.28和95％置信区间[CI]为1.06-1.55）。在完全调整的模型中，流产和人工流产的历史也与普遍的NAFLD风险增加相关（OR分别为1.84和95％CI，1.24-2.72; OR分别为1.23和95％CI，1.02-1.50）。结论：流产和人工流产均与中国中老年妇女普遍的NAFLD有关。 ？ 2013爱思唯尔公司

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