Inhospital morbidity and mortality among acute myeloid leukemia patients admitted for hematopoietic stem cell transplantation between 2002-2017

Saqib Abbasi; Joseph Bennett; Osama DiabGhulam Rehman MohyuddinAnurag Singh

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Inhospital morbidity and mortality among acute myeloid leukemia patients admitted for hematopoietic stem cell transplantation between 2002-2017

机译：急性髓细胞性白血病患者的院子里发病率和死亡率在2002 - 2017年之间接受造血干细胞移植。

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Acute myeloid leukemia (AML) is a disease with a poor prognosis, with a 28% 5-year survival rate. The incidence of AML increases with age which leads to an older population with multiple comor-bidities and inferior prognosis. Allogenic hematopoietic stem cell transplant (ASCT) remains the standard of care in most intermediate and high-risk AML patients. However, ASCT puts these patients at risk of severe cytopenia, opportunistic infections, acute graft versus host disease, and financial stress. These complications are particularly frequent during the early phases of treatment.

机译：急性髓样白血病（AML）是一种预后较差的疾病，5年生存率为28％。 AML的发生率随着年龄的增长而增加，这导致老年人群具有多种合并症和预后较低。在大多数中级和高危AML患者中，同种异性造血干细胞移植（ASCT）仍然是护理标准。但是，ASCT使这些患者处于严重的细胞质，机会性感染，急性移植与宿主疾病以及财务压力的危险中。在治疗的早期阶段，这些并发症特别频繁。

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来源
《Advances in cell and gene therapy.》 |2021年第3期|e112-e112|共1页
作者
Saqib Abbasi; Joseph Bennett; Osama DiabGhulam Rehman MohyuddinAnurag Singh;
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作者单位

Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City, USA;

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正文语种英语
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关键词
poor prognosis; At-risk; Acute Graft Versus Host DiseaseAcute Myelocytic LeukemiasHematopoietic Stem Cell TransplantationMyeloid leukemiaStandard of CareMortalityslurry phase treatmentStem Cell Transplantation;

机译：预后不良;处于危险中;急性移植与宿主疾病疾病;骨髓细胞性白血病丝网膜炎干细胞移植乳肌动物性白血病标准;毛细血管治疗相细胞治疗系统细胞移植;

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机译：Validação do Escore de Risco do EBmT em 1.084 pacientes portadores de leucemia mielóide crônica submetidos ao transplante alogênico de células precursoras hematopoiéticas no Brasil allogeneic hematopoietic stem cell transplantation - EBmT risk score validation in 1084 chronic myeloid leukemia patients transplanted in Brazil

Inhospital morbidity and mortality among acute myeloid leukemia patients admitted for hematopoietic stem cell transplantation between 2002-2017

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