...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of epidemiology >Individualized diagnosis interventions can add significant effectiveness in reducing human immunodeficiency virus incidence among men who have sex with men: Insights from Southern California
【24h】

Individualized diagnosis interventions can add significant effectiveness in reducing human immunodeficiency virus incidence among men who have sex with men: Insights from Southern California

机译：个性化诊断干预措施可以在减少与男性发生性关系的男性中降低人类免疫缺陷病毒的发病率方面显着提高有效性：南加州的见解

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: In this article, we examine the effectiveness of a variety of HIV diagnosis interventions in recently HIV-diagnosed men who have sex with men (MSM). These interventions use the preventive potential of postdiagnosis behavior change (PDBC), as measured by the reduction in the number of new infections. Empirical evidence for PDBC was presented in the behavioral substudy of the Southern California Acute Infection and Early Disease Research Program. In previous modeling work, we demonstrated the existing preventive effects of PDBC. However, a large proportion of new infections among MSM are either undiagnosed or diagnosed late, and the preventive potential of PDBC is not fully utilized. Methods: We derive empirical, stochastic, network-based models to examine the effectiveness of several diagnosis interventions that account for PDBC among MSM over a 10-year period. These interventions involve tests with shorter detection windows, more frequent testing, and individualized testing regimens. Results: We find that individualized testing interventions (i.e., testing individuals every three partners or 3months, whichever is first, or every six partners or 6months, whichever is first) result in significantly fewer new HIV infections than the generalized interventions we consider. Conclusions: This work highlights the potential of individualized interventions for new public health policies in HIV prevention.
机译：目的：在本文中，我们研究了各种HIV诊断干预措施在最近经HIV确诊的男男性接触者中的有效性。这些干预措施使用了诊断后行为改变（PDBC）的预防潜力，以新感染数量的减少来衡量。 PDBC的经验证据已在南加州急性感染和早期疾病研究计划的行为子研究中提供。在以前的建模工作中，我们演示了PDBC的现有预防作用。但是，MSM中新感染的大部分未得到诊断或诊断较晚，PDBC的预防潜力尚未得到充分利用。方法：我们得出基于经验，随机，基于网络的模型，以检查在10年内占MSM中PDBC的几种诊断干预措施的有效性。这些干预措施包括检测窗口更短，测试频率更高以及个性化测试方案的测试。结果：我们发现个性化测试干预措施（即，每三个伙伴或三个月（以较早者为准）或每六个伙伴或六个月或六个月（以较早者为准）中的一个个体）导致的艾滋病毒新感染人数明显少于我们考虑的广义干预措施。结论：这项工作突出了针对艾滋病毒预防的新公共卫生政策的个性化干预措施的潜力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号