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首页> 外文期刊>Annals of epidemiology >Social engagement and the risk of cardiovascular disease mortality: results of a prospective population-based study of older men.
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Social engagement and the risk of cardiovascular disease mortality: results of a prospective population-based study of older men.

机译:社会参与和心血管疾病死亡的风险:一项针对老年人的前瞻性人群研究结果。

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PURPOSE: To examine the prospective relation of social engagement with cardiovascular disease (CVD) mortality, taking into account behavioral factors (smoking, physical activity, body weight, and alcohol consumption), socioeconomic factors, and presence of comorbidity and disability. METHODS: A socioeconomically representative cohort of 5925 men aged 52-74 years from 24 British towns was followed up from 1992-2006. A scale from 0-9 was used based on questions reflecting the frequency and extent of social engagement in 1992. RESULTS: CVD mortality risk decreased with increasing social engagement score-age-adjusted hazard ratio (HR) for those with the highest social engagement score of 8-9 was 0.42 (95% confidence interval [95%CI], 0.32-0.53) compared to those with the lowest scores of 0-3 (p for trend or = 0.0001). Further adjustment for behavioral factors (smoking, alcohol, physical activity, and body weight), disability, comorbidity, and socioeconomic factors reduced the strength of this association, although strong evidence of an association remained: HR 0.70 (95%CI, 0.53-0.93) for highest versus lowest social engagement scores (p for trend = 0.0004). Although the association appeared somewhat stronger in subjects with preexisting CVD (HR 0.59 for highest vs. lowest social engagement scores) than in those without (HR 0.79), there was no evidence of an interaction between social engagement and preexisting CVD (p = 0.61). CONCLUSIONS: In our study of older men, social engagement appeared to have a modest protective effect on CVD mortality independent of behavioral factors, socioeconomic conditions, disease, and disability.
机译:目的:检查社会参与与心血管疾病(CVD)死亡率的预期关系,并考虑行为因素(吸烟,体育锻炼,体重和饮酒),社会经济因素以及合并症和残疾的存在。方法:从1992年至2006年,对来自24个英国城镇的5925名年龄在52-74岁的男性进行了社会经济代表性研究。根据反映1992年社会参与的频率和程度的问题,使用0-9的量表。结果:对于社会参与得分最高的人群,CVD死亡率风险随社会参与得分-年龄调整后的危险比(HR)的增加而降低。 8-9的得分为0.42(95%的置信区间[95%CI],0.32-0.53),得分最低的得分为0-3(趋势<或= 0.0001的p)。行为因素(吸烟,饮酒,体育锻炼和体重),残疾,合并症和社会经济因素的进一步调整降低了这种关联的强度,尽管仍然存在关联的有力证据:HR 0.70(95%CI,0.53-0.93) ),以获取最高和最低的社交参与度得分(趋势p = 0.0004)。尽管在已有CVD的受试者中社交联系得分最高(HR 0.59最高与最低社交参与得分)较没有CVD的受试者(HR 0.79)有关联,但没有证据表明社交参与与已有CVD之间存在交互作用(p = 0.61) 。结论:在我们对老年男性的研究中,社交参与似乎对CVD死亡率具有适度的保护作用,而与行为因素,社会经济状况,疾病和残疾无关。

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