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首页> 外文期刊>Annals of epidemiology >Arthritis: Its prevalence, Risk factors, And association with cardiovascular diseases in the United States, 1999 to 2008
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Arthritis: Its prevalence, Risk factors, And association with cardiovascular diseases in the United States, 1999 to 2008

机译：1999年至2008年，美国关节炎：其患病率，危险因素以及与心血管疾病的关系

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Objective: Arthritis is associated with cardiovascular diseases (CVDs). However, there are limited epidemiologic studies on arthritis in a national survey study. We therefore investigated the prevalence of self-reported arthritis and its association with CVDs. Methods: Data from 15,888 subjects aged 40 years or older in the United States National Health and Nutrition Examination Survey 1999 through 2008 were analyzed. CVD was defined as a self-reported history of heart attack, congestive heart failure, coronary heart disease, angina, or stroke. Results: The overall prevalence of self-reported arthritis in subjects aged 40 years or older increased from 33.5% in 1999 through 2000 to 37.0% in 2007 through 2008 (P for trend = 0.017). Among subjects with arthritis in 1999 through 2008, 35.3% had osteoarthritis (OA), 17.9% had rheumatoid arthritis (RA), and 10.2% had other types of arthritis, but 36.6% were unaware of their type of arthritis. Compared with subjects without OA, subjects with OA had higher odds for CVDs (odds ratio [OR], 1.53; P < .001), especially angina (OR, 2.18: P < .001). Compared with subjects without RA, subjects with RA had higher odds for CVDs (adjusted OR, 2.39; P < .001), especially congestive heart failure (OR, 3.59; P < .001). Conclusions: Both RA and OA are strongly associated with CVDs in the general population. Further studies are needed to investigate their causal relationship. ? 2013 Elsevier Inc.
机译：目的：关节炎与心血管疾病（CVD）有关。但是，在一项全国性的调查研究中，关于关节炎的流行病学研究有限。因此，我们调查了自我报告的关节炎的患病率及其与CVD的关系。方法：分析了1999年至2008年美国国家健康与营养调查中15888名40岁以上的受试者的数据。 CVD被定义为自我报告的心脏病发作，充血性心力衰竭，冠心病，心绞痛或中风的病史。结果：40岁及以上受试者自我报告的关节炎总患病率从1999年的2000年的33.5％增加到2000年的2007年的2008年的37.0％（趋势P = 0.017）。在1999年至2008年患有关节炎的受试者中，骨关节炎（OA）占35.3％，类风湿关节炎（RA）占17.9％，其他类型的关节炎占10.2％，但是有36.6％的人不知道自己的关节炎类型。与没有OA的受试者相比，患有OA的受试者的CVD机率更高（优势比[OR]为1.53; P <.001），尤其是心绞痛（OR为2.18：P <.001）。与没有RA的受试者相比，患有RA的受试者的CVD机率更高（校正后的OR，2.39; P <.001），尤其是充血性心力衰竭（OR，3.59; P <.001）。结论：RA和OA都与普通人群的CVD密切相关。需要进一步研究以调查其因果关系。 ？ 2013爱思唯尔公司

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