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首页> 外文期刊>Annals of epidemiology >Electrolyte intake and nonpharmacologic blood pressure control.
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Electrolyte intake and nonpharmacologic blood pressure control.

机译：电解质摄入和非药物性血压控制。

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PURPOSE: To characterize relationships between sodium and potassium intakes and blood pressure control.METHODS: We analyzed repeated 24-hour diet recalls and 24-hour urine assays from 873 elderly participants with established hypertension in a 3-year clinical trial of lifestyle interventions. Pooled estimates of electrolyte intakes were developed using hierarchical measurement error models and related to nonpharmacologic blood pressure control.RESULTS: Relative decreases in sodium and increases in potassium intakes each had graded relationships with better blood pressure control. After adjustment for measurement error, a 100 mmol/24-hour decrease in sodium intake was associated with an odds ratio of 2.93 [95% confidence interval: 1.83, 4.64] for maintaining nonpharmacologic blood pressure control throughout follow-up. A 50 mmol/24-hour increase in potassium intake was associated with an odds ratio of 2.00 [1.12, 3.55]. These relationships were independent of each other and of baseline levels of intakes. Blood pressure control was most strongly associated with sodium intake for participants with lower systolic blood pressures and longer duration of hypertension, and with potassium for those with elevated diastolic blood pressures.CONCLUSIONS: Sodium and potassium intakes exert independent graded influences on nonpharmacologic blood pressure control. Correlated measurement error may spuriously introduce a dependency among these relationships.
机译：目的：表征钠和钾的摄入量与血压控制之间的关系。方法：在一项为期3年的生活方式干预临床试验中，我们分析了873名患有高血压的老年参与者的重复24小时饮食回想和24小时尿液分析。电解质摄入量的汇总估计值是使用分层测量误差模型开发的，并且与非药物性血压控制有关。调整测量误差后，钠摄入量每减少100 mmol / 24小时，比值比为2.93 [95％置信区间：1.83、4.64]，以在整个随访期间维持非药物性血压控制。钾摄入量每增加50 mmol / 24小时，比值比为2.00 [1.12，3.55]。这些关系彼此独立并且与摄入量的基线水平无关。血压控制与收缩压较低，高血压持续时间较长的参与者的钠摄入量密切相关，而舒张压升高的参与者与钾的摄入量密切相关。结论：钠和钾的摄入量对非药物性血压控制具有独立的分级影响。相关的测量误差可能会在这些关系之间虚假地引入依赖性。

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