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首页> 外文期刊>Annals of epidemiology >Low risk of hip fracture among elderly breast cancer survivors.
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Low risk of hip fracture among elderly breast cancer survivors.

机译：老年乳腺癌幸存者中髋部骨折的风险低。

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PURPOSE: Prior research has shown that women with either osteoporotic fracture or low bone density are at a decreased risk of breast cancer. Little prior work has evaluated whether women with breast cancer are at a decreased risk of osteoporotic fracture. METHODS: We used data from the National Cancer Institute's Surveillance Epidemiology and End Results (SEER)-Medicare program to study the risk of hip fracture among elderly female Medicare beneficiaries with and without histories of breast cancer. Using the SEER file, we identified elderly women survivors of stage 0, I, or II breast cancer (N=5980) diagnosed between the ages of 55 and 64 years; using the Medicare 5% file, we identified elderly women without histories of cancer (N=23,165) from SEER regions. Using Medicare claims from 1993 through 1998, we followed women for hospitalization for hip fracture or death until December 31, 1998. RESULTS: We found the rate ratio of hospitalization for hip fracture for breast cancer survivors relative to comparison patients was 0.63 (95% CI: 0.43-0.94) after adjusting for age, race, socioeconomic status, geographic location, cohort entry year, and medical comorbidity. CONCLUSIONS: We conclude that survivors of early stage post-menopausal breast cancer are at significantly lower risk of hip fracture than women who do not have histories of breast cancer.
机译：目的：先前的研究表明，患有骨质疏松性骨折或骨密度低的女性患乳腺癌的风险降低。很少有先前的工作评估过乳腺癌女性是否患骨质疏松性骨折的风险降低。方法：我们使用了美国国家癌症研究所的监测流行病学和最终结果（SEER）-医疗保险计划的数据，研究了有或没有乳腺癌史的老年女性医疗保险受益人的髋部骨折风险。使用SEER文件，我们确定了被诊断为55至64岁的0，I或II期乳腺癌（N = 5980）的老年女性幸存者;使用Medicare 5％档案，我们从SEER地区确定了无癌症史的老年妇女（N = 23,165）。使用1993年至1998年的Medicare索赔，我们追踪了因髋部骨折或死亡而住院的妇女，直到1998年12月31日。结果：我们发现，乳腺癌幸存者相对于比较患者的髋部骨折住院率为0.63（95％CI ：0.43-0.94），然后调整年龄，种族，社会经济地位，地理位置，入组年份和合并症。结论：我们得出结论，绝经后早期乳腺癌的幸存者比没有乳腺癌史的女性的髋部骨折风险要低得多。

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