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首页> 外文期刊>Annals of epidemiology >Determinants of progression to AIDS or death after HIV diagnosis, United States, 1996 to 2001.
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Determinants of progression to AIDS or death after HIV diagnosis, United States, 1996 to 2001.

机译：美国，1996年至2001年，决定了艾滋病进展为艾滋病或诊断为艾滋病的死亡。

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PURPOSE: The aim of the study is to determine factors associated with disease progression after human immunodeficiency virus (HIV) infection diagnosis. METHODS: We applied generalized linear models with Poisson errors to obtain adjusted relative excess risk for death for persons diagnosed with acquired immunodeficiency syndrome (AIDS) or HIV infection (with or without concurrent AIDS) during 1996 to 2001. We examined differences in time between HIV diagnosis and AIDS by using standardized Kaplan-Meier survival methods. RESULTS: Relative excess risk for death within 3 years after AIDS diagnosis was significantly greater for non-Hispanic blacks (1.15; 95% confidence interval [CI], 1.12-1.18), American Indians (1.33; 95% CI, 1.16-1.52), and Hispanics (1.16; 95% CI, 1.13-1.20) compared with whites. Risk for death also was greater among injection drug users (men, 1.50; 95% CI, 1.46-1.54; women, 1.57; 95% CI, 1.51-1.62) compared with men who have sex with men and among those diagnosed at older ages compared with younger persons. Similar disparities between groups in risk for death were observed from HIV diagnosis. Risk for progression from HIV to AIDS was greater for nonwhites, men, and older persons compared with whites, women, and younger persons, respectively. CONCLUSIONS: Interventions should target those at excess risk for death or morbidity to ensure access to quality care and adherence to treatment to slow disease progression.
机译：目的：本研究的目的是确定与人类免疫缺陷病毒（HIV）感染诊断后疾病进展相关的因素。方法：我们应用了带有Poisson误差的广义线性模型，以获取1996年至2001年诊断为获得性免疫缺陷综合症（AIDS）或HIV感染（有或没有并发AIDS）的人的调整过的相对死亡风险。我们研究了HIV之间的时间差异通过使用标准化的Kaplan-Meier生存方法进行诊断和艾滋病。结果：非西班牙裔黑人（1.15; 95％置信区间[CI]，1.12-1.18），美洲印第安人（1.33; 95％CI，1.16-1.52）艾滋病诊断后3年内的相对死亡风险显着更高。和西班牙裔（1.16; 95％CI，1.13-1.20）与白人相比。与男男性接触者和年龄较大的男性相比，注射吸毒者的死亡风险也更高（男性为1.50; 95％CI为1.46-1.54;女性为1.57; 95％CI为1.51-1.62）。与年轻人相比。从艾滋病毒的诊断中可以看出，死亡风险的人群之间存在相似的差异。与白人，妇女和年轻人相比，非白人，男子和老年人从艾滋病毒演变成艾滋病的风险分别更大。结论：干预应针对那些死亡或发病风险较高的人群，以确保获得优质护理并坚持治疗以减缓疾病进展。

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