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首页> 外文期刊>Annals of epidemiology >Waist-hip-ratio as a predictor of all-cause mortality in high-functioning older adults.
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Waist-hip-ratio as a predictor of all-cause mortality in high-functioning older adults.

机译:腰臀比可预测高功能老年人的全因死亡率。

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PURPOSE: The relationship between obesity and mortality in older adults is debated, with concern that body mass index (BMI) may be an imperfect measure of obesity in this age group. We assessed the relationship between three measures of obesity and all-cause mortality in a group of healthy older adults. METHODS: We analyzed data from the MacArthur Successful Aging Study, a longitudinal study of high-functioning men and women, ages 70-79 years at baseline. We examined 12-year, all-cause mortality risk by BMI, waist circumference, and waist-to-hip circumference ratio (WHR). Proportional hazards regression was used to adjust for gender, race, baseline age, and smoking status. We tested for obesity interactions with gender, race, and smoking status and conducted stratified analyses based on the results of interaction testing. RESULTS: There was no association between all-cause mortality and BMI or waist circumference in either unadjusted or adjusted analyses. In contrast, all-cause mortality increased with WHR. There was an interaction with sex, so that there was a graded relationship between WHR and mortality in women (relative hazard, 1.28 per 0.1 increase in WHR; 95% confidence interval, 1.05-1.55) and a threshold relationship in men (relative hazard 1.75 for WHR>1.0 compared to WHR< or =1.0; 95% confidence interval, 1.06-2.91). CONCLUSION: WHR rather than BMI appears to be the more appropriate yardstick for risk stratification of high-functioning older adults.
机译:目的:辩论肥胖与老年人死亡率之间的关系,担心体重指数(BMI)可能是该年龄段肥胖的不完美指标。我们评估了一组健康的老年人中肥胖的三种测量与全因死亡率之间的关系。方法:我们分析了MacArthur成功的衰老研究的数据,该研究是基线时年龄在70-79岁的高功能男性和女性的纵向研究。我们通过BMI,腰围和腰臀围比率(WHR)检查了12年全因死亡率风险。比例危害回归用于调整性​​别,种族,基线年龄和吸烟状况。我们测试了肥胖与性别,种族和吸烟状况的相互作用,并根据相互作用测试的结果进行了分层分析。结果:无论是未经调整还是经过调整的分析,全因死亡率与BMI或腰围均无关联。相反,全因死亡率随WHR增加。与性别之间存在相互作用,因此女性的WHR与死亡率之间存在分级关系(相对危险度,WHR每增加0.1则增加1.28; 95%置信区间1.05-1.55),而男性具有阈值关系(相对危险度1.75)与WHR <或= 1.0相比,WHR> 1.0; 95%置信区间1.06-2.91)。结论:WHR而非BMI似乎是高功能老年人风险分层的更合适标准。

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