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首页> 外文期刊>Annals of epidemiology >Coronary Death and Myocardial Infarction among Hispanics in the Northern Manhattan Study: Exploring the Hispanic Paradox
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Coronary Death and Myocardial Infarction among Hispanics in the Northern Manhattan Study: Exploring the Hispanic Paradox

机译：曼哈顿北部研究中西班牙裔人群中的冠心病死亡和心肌梗塞：探讨西班牙裔悖论

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Purpose: Prior studies have reported that Hispanics have lower cardiovascular disease (CVD) mortality despite a higher burden of risk factors. We examined whether Hispanic ethnicity was associated with a lower risk of nonfatal myocardial infarction (MI) coronary death (CD) and vascular death. Methods: A total of 2671 participants in the Northern Manhattan Study without clinical CVD were prospectively evaluated. Cox models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for the association of race-ethnicity with nonfatal MI, CD, and vascular death after adjusting for demographic and CVD risk factors. Results: Mean age was 68.8 (10.4) years; 52.8% were Hispanic (88% Caribbean-Hispanic). Hispanics were more likely to have hypertension (73.1% vs. 62.2%, p < .001) and diabetes (22.0% vs. 13.3%, p < .001), and less likely to perform any physical activity (50.1% vs. 69.2%, p < .001) compared to non-Hispanic whites (NHW). During a mean 10 years of follow-up there were 154 nonfatal MIs, 186 CD, and 386 vascular deaths. In fully adjusted models, Hispanics had a lower risk of CD (adjusted HR = 0.36, 95% CI: 0.21-0.60), and vascular death (adjusted HR = 0.62, 95% CI: 0.43-0.89), but not nonfatal MI (adjusted HR = 0.95, 95% CI: 0.56-1.60) when compared to NHW. Conclusions: We found a "Hispanic paradox" for coronary and vascular deaths, but not nonfatal MI.
机译：目的：先前的研究报告说，尽管危险因素的负担增加，西班牙裔美国人的心血管疾病（CVD）死亡率却较低。我们检查了西班牙裔是否与非致命性心肌梗死（MI）冠状动脉死亡（CD）和血管死亡的较低风险相关。方法：前瞻性评估了北部曼哈顿研究中共2671名没有临床CVD的参与者。校正人口统计学和CVD危险因素后，使用Cox模型计算种族比与非致命MI，CD和血管死亡的关联的危险比（HR）和95％置信区间（CI）。结果：平均年龄为68.8（10.4）岁;西班牙裔占52.8％（加勒比海裔占88％）。西班牙裔美国人更有可能患高血压（73.1％vs. 62.2％，p <.001）和糖尿病（22.0％vs. 13.3％，p <.001），而从事任何体育活动的可能性较小（50.1％vs. 69.2） ％，p <.001）与非西班牙裔白人（NHW）相比。在平均10年的随访期间，有154例非致命性MI，186例CD和386例血管死亡。在完全调整的模型中，西班牙裔患者有较低的CD风险（调整后的HR = 0.36，95％CI：0.21-0.60）和血管性死亡（调整后的HR = 0.62，95％CI：0.43-0.89），但非致命性MI风险较低（与NHW相比，调整后的HR = 0.95，95％CI：0.56-1.60）。结论：我们发现了冠心病和血管性死亡的“西班牙悖论”，而非非致命性心肌梗死。

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