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首页> 外文期刊>Behavioural pharmacology >Effects of amphetamine on differential reinforcement of low rates of responding.
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Effects of amphetamine on differential reinforcement of low rates of responding.

机译：苯丙胺对低反应率差异增强的影响。

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A multiple differential reinforcement of low rate 8 s discrete-trial, differential reinforcement of low rate 8 s free-operant procedure was used to investigate the effects of D-amphetamine on interval timing in pigeons. On the discrete trial differential reinforcement of low rate early responses terminated the trial; on the free-operant differential reinforcement of low rate early responses reset the reinforcement timer but had no other effects. Frequency distributions of log interevent times for responses following reinforcement on both the free-operant and discrete-trial components showed a single-peaked distribution. The interevent time distribution for responses preceded by unreinforced responses on the free-operant differential reinforcement of low rate showed two peaks. The pigeons were administered two doses of D-amphetamine for 20 successive sessions. The means of interevent time distributions did not change under drug for either condition but widths of the distributions increased in both conditions and for both types of interevent times in the free-operant differential reinforcement of low rate. In the free-operant condition the mean interevent time for responses preceded by prior responses declined significantly with drug owing to a reduction in the proportion of responses in the shorter interevent time distribution. In effect, response bouts were shortened by drug administration. The rate-dependent hypothesis well described the effect of amphetamine on responses in the free-operant procedure. These results are discussed in the context of amphetamine's effects on the temporal structure of behavior.
机译：低速8 s离散试验的多重微分补强，低速8 s自由操作程序的微分补强用于研究D-苯丙胺对鸽子间隔时间的影响。在离散试验中，低速早期反应的差异强化终止了试验;对低速率的自由操作差分补强，早期响应重置了补强计时器，但没有其他影响。自由操作和离散试用组件都得到增强后，响应的对数间隔时间的频率分布显示出单峰分布。在低速率的自由操作微分补强下，响应的事件间时间分布先于未增强的响应，出现两个峰值。连续20次给鸽子服用两剂D-苯异丙胺。在两种情况下，药物间期时间分布的均值均未改变，但在两种情况下以及两种类型的间期时间中，低速自由差动补强的分布宽度均增加。在自由操作者条件下，药物的平均事件间隔时间显着下降，这是由于在较短的事件间隔时间分布中，响应的比例降低了。实际上，通过给药可以缩短反应周期。速率依赖性假说很好地描述了苯丙胺对自由手术程序反应的影响。在苯丙胺对行为的时间结构的影响的背景下讨论了这些结果。

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