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首页> 外文期刊>ANZ journal of surgery >Predictors of breast cancer in women recalled following screening.
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Predictors of breast cancer in women recalled following screening.

机译：筛查后回顾了女性乳腺癌的预测指标。

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BACKGROUND: Established risk factors are associated with between 25 and 56% of breast cancer cases, but the relative importance and relevance to different age groups is unclear. METHODS: This case-control study examines established risk factors in 298 women with breast cancer and 1926 women without breast cancer aged 40-87 who were recalled for assessment following routine mammography. RESULTS: The cancer group were significantly older than the non-cancer group (F1,222 = 107.6; P < 0.0001). Postmenopausal obesity increased the odds of developing breast cancer (OR: 2.35; CI: 1.33-4.16). The breast cancer group were more likely to have used oral contraceptives (OR: 1.50; CI: 1.09-2.05), and women who used contraceptives for more than 10 years in total were at the highest risk (OR: 1.73; CI: 1.13-2.65). Daily consumption of alcohol was also associated with increased risk of developing breast cancer (OR: 1.62; CI: 1.13-2.33). Reproductive factors and a family history of breast cancer did not affect the odds of developing breast cancer and the reasons for these findings are explored. CONCLUSIONS: Results suggest that the effects of weight reduction in reducing postmenopausal breast cancer risk should be assessed.
机译：背景：既定的危险因素与25％至56％的乳腺癌病例相关，但不清楚与不同年龄组的相对重要性和相关性。方法：本病例对照研究检查了298例乳腺癌女性和1926例40-87岁无乳腺癌女性的既定危险因素，这些妇女在常规乳腺X线摄影后被召回进行评估。结果：癌症组的年龄明显高于非癌组（F1,222 = 107.6; P <0.0001）。绝经后肥胖增加患乳腺癌的几率（OR：2.35; CI：1.33-4.16）。乳腺癌组使用口服避孕药的可能性更高（OR：1.50; CI：1.09-2.05），并且使用避孕工具的妇女总计超过10年的风险最高（OR：1.73; CI：1.13- 2.65）。每天饮酒还增加了患乳腺癌的风险（OR：1.62; CI：1.13-2.33）。生殖因素和乳腺癌家族史不影响患乳腺癌的几率，并探讨了这些发现的原因。结论：结果提示，应评估减轻体重对降低绝经后乳腺癌风险的影响。

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