Greater Mechanical Loading During Walking Is Associated With Less Collagen Turnover in Individuals With Anterior Cruciate Ligament Reconstruction

Pietrosimone Brian; Blackburn J. Troy; Harkey Matthew S.; Luc Brittney A.; Hackney Anthony C.; Padua Darin A.; Driban Jeffrey B.; Spang Jeffrey T.; Jordan Joanne M.

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Greater Mechanical Loading During Walking Is Associated With Less Collagen Turnover in Individuals With Anterior Cruciate Ligament Reconstruction

机译：前交叉韧带重建患者行走过程中更大的机械负荷与较少的胶原蛋白流失相关

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Background: Individuals who have sustained an anterior cruciate ligament (ACL) injury and undergo ACL reconstruction (ACLR) are at higher risk of developing knee osteoarthritis. It is hypothesized that altered knee loading may influence the underlying joint metabolism and hasten development of posttraumatic knee osteoarthritis.

机译：背景：遭受前交叉韧带（ACL）损伤并接受ACL重建（ACLR）的个体患膝骨关节炎的风险较高。据推测，改变膝关节负荷可能会影响潜在的关节代谢并加速创伤后膝关节骨关节炎的发展。

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来源
《American Journal of Sports Medicine》 |2016年第2期|共8页
作者
Pietrosimone Brian; Blackburn J. Troy; Harkey Matthew S.; Luc Brittney A.; Hackney Anthony C.; Padua Darin A.; Driban Jeffrey B.; Spang Jeffrey T.; Jordan Joanne M.;
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正文语种 eng
中图分类运动医学;
关键词
osteoarthritis; knee; posttraumatic; cartilage; ground-reaction force;

机译：骨关节炎;膝盖;创伤后;软骨;地面反应力;

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1. Greater Mechanical Loading During Walking Is Associated With Less Collagen Turnover in Individuals With Anterior Cruciate Ligament Reconstruction [J] . Pietrosimone Brian, Blackburn J. Troy, Harkey Matthew S., American Journal of Sports Medicine . 2016,第2期

机译：前交叉韧带重建患者行走过程中更大的机械负荷与较少的胶原蛋白流失相关
2. GREATER PEAK VERTICAL GROUND REACTION FORCE AND VERTICAL GROUND REACTION FORCE LOADING RATE DURING WALKING GAIT ARE ASSOCIATED WITH A LOWER SERUM RATIO OF COLLAGEN TURNOVER IN INDIVIDUALS WITH ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION [J] . Pietrosimone B., Blackburn J. T., Harkey M. S., Osteoarthritis and cartilage . 2015,第Suppla2期

机译：在步行步态期间，垂直峰值垂直地反作用力和垂直地反应力负载率与患有前十字架韧带重建的个体中胶原蛋白周转的较低血清比相关
3. Lesser lower extremity mechanical loading associates with a greater increase in serum cartilage oligomeric matrix protein following walking in individuals with anterior cruciate ligament reconstruction [J] . Brittney A. Luc-Harkey, Jason R. Franz, Anthony C. Hackney, Clinical biomechanics . 2018,第期

机译：较小的下肢机械载荷伴侣患者血清软骨寡聚基质蛋白质较大，在患有前十字韧带重建的个体后
4. Biomechanical Analysis of Knee Cartilage Stress for Individuals With Anterior Cruciate Ligament Reconstruction [C] . N. H. Yang, L C. Tsai, C. M. Powers ASME summer bioengineering conference;SBC2010 . 2010

机译：前交叉韧带重建患者膝关节软骨应力的生物力学分析
5. Acute Effect of Altered Mechanical Loading on Biomechanics and Biochemical Markers in Individuals with Anterior Cruciate Ligament Reconstruction [D] . Harkey, Brittney A. 2017

机译：改变机械加载在胎儿韧带重建中胞胎生物力学和生化标志物的急性作用
6. Body Mass Index and Type 2 Collagen Turnover in Individuals After Anterior Cruciate Ligament Reconstruction [O] . Amy R. Lane, Matthew S. Harkey, Hope C. Davis, 2019

机译：前十字韧带重建后个体的体重指数和2型胶原蛋白的转变
7. Greater peak vertical ground reaction force and vertical ground reaction force loading rate during walking gait are associated with a lower serum ratio of collagen turnover in individuals with anterior cruciate ligament reconstruction [O] . Pietrosimone B., Blackburn J.T., Harkey M.S., 2015

机译：步行步态时垂直地面反作用力峰值和垂直地面反作用力负荷率较高与前交叉韧带重建个体的胶原周转率较低有关

Greater Mechanical Loading During Walking Is Associated With Less Collagen Turnover in Individuals With Anterior Cruciate Ligament Reconstruction

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