Evidence that Extreme Dilutions of Paclitaxel and Docetaxel Alter Gene Expression of In Vitro Breast Cancer Cells

Seker Sinem; Guven Celal; Akcakaya HandanBahtiyar NurtenAkbas FahriOnaran Ilhan

首页> 外文期刊>Homeopathy: the journal of the Faculty of Homeopathy >Evidence that Extreme Dilutions of Paclitaxel and Docetaxel Alter Gene Expression of In Vitro Breast Cancer Cells

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Evidence that Extreme Dilutions of Paclitaxel and Docetaxel Alter Gene Expression of In Vitro Breast Cancer Cells

机译：紫杉醇和多西他赛的极端稀释的证据改变了体外乳腺癌细胞的基因表达

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Background Gene expression analysis of cells treated with extreme dilutions or micro amounts of drugs has been used to provide useful suggestions about biological responses. However, most of the previous studies were performed on medicines being prepared from a variety of herbal and metal sources. This study investigated the effects of ultramolecular dilution of the taxane anti-cancer drugs, which are not commonly used in homeopathic medicines, on mRNA expression profiles of five key genes (p53, p21, COX-2, TUBB2A and TUBB3) in the breast cancer cell line MCF-7.

机译：用极稀释剂或微量药物处理的细胞的背景基因表达分析已用于提供有关生物学反应的有用建议。但是，以前的大多数研究都是关于从多种草药和金属来源准备的药物进行的。这项研究调查了紫杉烷抗癌药物的超分子稀释剂的影响，这些药物不常用于顺势疗法药物，对五个关键基因（p53，p21，cox，cox-2，tubb2a和tubb3）的mRNA表达曲线的影响细胞系MCF-7。

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《Homeopathy: the journal of the Faculty of Homeopathy》 |2018年第1期|32-39|共8页
作者
Seker Sinem; Guven Celal; Akcakaya HandanBahtiyar NurtenAkbas FahriOnaran Ilhan;
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作者单位

Bezmialem Vakif Univ, Fac Med, Dept Med Biol, Istanbul, Turkey;

Adiyaman Univ, Fac Med, Dept Biophys, Adiyaman, Turkey;

Istanbul Univ, Cerrahpasa Fac Med, Dept Med Biol, Istanbul, TurkeyIstanbul Univ, Cerrahpasa Fac Med, Dept Biophys, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Dept Biophys, Istanbul, Turkey;

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正文语种英语
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TUBB3 gene; Homeopathic Remedies; Homeopathybreast cancer cell linedocetaxelTaxoidsPharmaceutical PreparationsPaclitaxel;

机译：TUBB3基因;顺势疗法;顺势疗法癌细胞衬有甲状腺素固定剂药物剂甲甲酰胺;

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Evidence that Extreme Dilutions of Paclitaxel and Docetaxel Alter Gene Expression of In Vitro Breast Cancer Cells

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