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首页> 外文期刊>Otology and neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology >Histopathology After Endolymphatic Sac Surgery for Meniere's Syndrome
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Histopathology After Endolymphatic Sac Surgery for Meniere's Syndrome

机译：梅尼尔综合征内淋巴囊后的组织病理学

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摘要

Background: The putative goal of sac surgery in Meniere's syndrome is to promote the flow of endolymph from the labyrinth to the endolymphatic sac and thereby relieving hydrops. There are scant published histopathologic data whether sac surgery actually accomplishes this goal.Objective: To determine whether sac surgery relieves hydrops by examining the histopathologic changes in temporal bones obtained from individuals who had undergone sac surgery during life for Meniere's syndrome.Methods: Temporal bones were examined from 15 patients who had sac surgery. Data on the presence and severity of hydrops, histology of the sac, and whether the procedure relieved vertigo were collected.Results: The surgery failed to expose the sac in 5 cases; 4 of the 5 had relief from vertigo. The sac was exposed, but the shunt failed to reach the lumen of the sac in 8 cases; 4 of the 8 had relief from vertigo. The shunt was successfully placed within the lumen of the sac in 2 cases; both cases failed to experience relief from vertigo. Endolymphatic hydrops was present in all 15 cases. Conclusion: Endolymphatic sac surgery does not relieve hydrops in patients with Meniere's syndrome. Yet, sac surgery relieves vertigo in some patients, but the mechanism of such symptomatic relief remains unknown.
机译：背景：Meniere综合征中SAC手术的推定目标是促进内淋巴从迷宫流向内淋巴结囊，从而减轻水力流。有很少发表的组织病理学数据是否真正实现了这一目标。目标：确定SAC手术是否通过检查从生命中接受囊囊的个体从Meniere综合征进行囊囊手术的个体中获得的颞骨骨骼的组织病理学变化来缓解水力发像。检查了15例患有SAC手术的患者。有关水力学的存在和严重程度，囊病的组织学以及是否解除了眩晕的数据。分泌：手术未能在5例中暴露SAC; 5中的4个从Vertigo那里解脱出来。 SAC暴露了，但分流器在8例中未能到达SAC的腔内; 8中的4个从Vertigo那里解脱出来。分流在2例中成功地放置在SAC的腔内;这两种情况都没有从Vertigo体验出来。在所有15例病例中均存在内淋巴水流。结论：内形囊囊手术不能缓解梅尼尔综合征患者的水力。然而，SAC手术可缓解某些患者的眩晕，但这种症状缓解的机制仍然未知。

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