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Peptide inhibitors against influenza virus.

机译:抗流感病毒的肽抑制剂。

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Influenza A virus is a particularly problematic virus because of its ability to cause high levels of morbidity on a global scale within a remarkably short period of time. It also has the potential to kill very large numbers of people as occurred in the Spanish influenza pandemic in 1918. Options for antiviral therapy are limited because of the paucity of available drugs and the rapid mutation rate of the virus leading to the emergence of drug-resistant strains. The current H1N1 pandemic and potential threats posed by other strains highlight the need to develop novel therapeutic and prophylactic strategies. Here, we summarize the current state and recent developments of peptide-based inhibitors of influenza A virus.
机译:甲型流感病毒是一种特别成问题的病毒,因为它能够在极短的时间内在全球范围内引起高水平的发病率。它也具有杀死1918年西班牙流感大流行中大量人的潜力。由于可用药物的匮乏以及病毒的快速突变率导致药物的出现,抗病毒治疗的选择受到限制。抗性菌株。当前的H1N1大流行和其他菌株造成的潜在威胁凸显了开发新的治疗和预防策略的必要性。在这里,我们总结了基于肽的甲型流感病毒抑制剂的现状和最新进展。

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