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首页> 外文期刊>Blood Pressure Monitoring >Effects of isometric handgrip training on blood pressure (resting and 24 h ambulatory) and heart rate variability in medicated hypertensive patients.
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Effects of isometric handgrip training on blood pressure (resting and 24 h ambulatory) and heart rate variability in medicated hypertensive patients.

机译：等距把手训练对药物性高血压患者的血压（静息和24 h动态卧床）和心率变异性的影响。

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摘要

Isometric handgrip (IHG) training (four, 2-min sustained contractions at 30% of maximal voluntary contraction, three times per week for 8-10 weeks) lowers resting arterial blood pressure (BP) in hypertensive patients, including those receiving pharmacotherapy, although the mechanisms remain elusive. Ambulatory BP measurements are more efficacious in predicting cardiovascular disease-related events, yet the effects of IHG training on ambulatory BP are unknown. The objective of the current investigation was to test the hypotheses that 8 weeks of IHG training lowers resting and 24 h ambulatory BP concomitantly in medicated hypertensive patients, and may be the result of improved vagal modulation.BP was assessed using brachial artery oscillometry, and coarse-graining spectral analysis was used to determine spectral power. Resting and 24 h ambulatory BP and heart rate variability (HRV) were measured pretraining, midtraining, and post-training in 11 medicated hypertensive patients (mean ± SD, resting BP: 113.9 ± 12.7/60.7 ± 11.6 mmHg), and in nine medicated hypertensive controls (resting BP: 117.8 ± 14.3/67.5 ± 4.2 mmHg).Indices of BP and HRV were not significantly altered with IHG training (all P > 0.05).IHG training does not lower resting or ambulatory BP in hypertensive patients successfully treated with pharmacotherapy to within the normal range (≤ 120/80 mmHg), nor does it improve HRV. Future studies should examine alternative IHG training protocols in well-managed hypertensive patients and/or target poorly controlled medicated hypertensive patients.
机译：等距握力训练（IHG）训练（以最大自愿收缩的30％进行4次2分钟持续收缩，每周3次，共8-10周）降低了高血压患者（包括接受药物治疗的患者）的静息动脉血压（BP）这些机制仍然难以捉摸。动态血压测量在预测心血管疾病相关事件方面更为有效，但IHG训练对动态血压的影响尚不清楚。本研究的目的是检验以下假设：药物性高血压患者在进行IHG训练8周后会同时降低静息和24 h动态血压，这可能是迷走神经调节改善的结果。采用肱动脉示波法和粗光谱分析用于确定光谱功率。在11名药物性高血压患者（平均±SD，静息BP：113.9±12.7 / 60.7±11.6 mmHg）和9个药物治疗的高血压患者的训练前，中训练和训练后测量其静息和24 h动态血压和心律变异性高血压对照组（静息BP：117.8±14.3 / 67.5±4.2 mmHg）。使用IHG训练后，血压和HRV的指标没有显着改变（所有P> 0.05）。使用IHG训练并不能降低成功治疗过高血压的患者的静息或动态BP药物治疗至正常范围（≤120/80 mmHg），也不会改善HRV。未来的研究应在管理良好的高血压患者和/或针对控制不良的药物性高血压患者中检查替代性IHG训练方案。

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