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首页> 外文期刊>Archives of general psychiatry. >Genetic and environmental influences on disordered gambling in men and women.
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Genetic and environmental influences on disordered gambling in men and women.

机译：遗传和环境影响无序赌博在男性和女性。

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CONTEXT: Women now represent nearly half of all individuals in treatment for pathological gambling (PG), but relatively little is known about the causes of PG among women or potential sex differences in the causes of PG. OBJECTIVES: To (1) investigate the role of genetic and environmental risk factors in the development of disordered gambling (DG) among women and (2) determine the extent to which the genetic and environmental risk of DG among women differs quantitatively or qualitatively from the risk of DG among men. (Disordered gambling refers to the full continuum of gambling-related problems that includes PG disorder.) DESIGN: Twin study. SETTING: The national community-based Australian Twin Registry. PARTICIPANTS: Four thousand seven hundred sixty-four individuals from 2889 twin pairs; twins were aged 32 to 43 years and 57% were women. Main Outcome Measure Disordered gambling was defined based on lifetime DSM-IV PG symptom counts. RESULTS: The estimate of the proportion of variation in liability for DG due to genetic influences was 49.2% (95% confidence interval, 26.7-60.9). There was no evidence for shared environmental influences contributing to variation in DG liability. There was no evidence for quantitative or qualitative sex differences in the causes of variation in DG liability. CONCLUSIONS: This study establishes for the first time that genes are as important in the etiology of DG in women as they are in men and that the susceptibility genes contributing to variation in liability for DG are likely to overlap considerably in men and women.
机译：背景:女性现在占将近一半的个人在治疗病态赌博(PG),但很少有人知道关于女性PG或潜在的原因性别差异在PG的原因。目的:(1)研究基因的作用环境发展的风险因素无序赌博女性(DG)和(2)确定了遗传和程度DG女性不同的环境风险定量或定性的风险男性DG。完整的连续的相关问题包括PG障碍。)设置:澳大利亚国家以社区为基础的双胞胎注册表。从2889年双胞胎数百六十四人双;是女性。赌博的定义基于dsm - iv PG一生症状。在DG责任比例的变化遗传的影响为49.2%(95%的信心区间,26.7 - -60.9)。共享环境影响导致DG的变化责任。定量或定性的性别差异DG的变化引起的责任。结论:本研究建立了第一时间,基因是重要的病因DG的女性和男性一样,易感基因导致的变化DG责任可能会重叠在男性和女性。

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