Fitting whole-genome sequencing analysis for metastasis

Julia Simundza

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Fitting whole-genome sequencing analysis for metastasis

机译：全基因组测序分析转移

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With the growing list of targeted cancer therapies and biomarkers, targeted next-generation sequencing panels may not be sufficient to identify the full spectrum of treatment options for precision oncology. Whole-genome sequencing offers a more comprehensive, yet costlier, alternative. Thus, more evidence is needed on how and when to implement this type of testing. By analyzing a large collection of paired metastasis biopsies, Voest and colleagues now find relatively limited genomic evolution when comparing whole-genome profiles of biopsies before and after standard-of-care therapy.

机译：越来越多的有针对性的癌症疗法和生物标志物,有针对性的下一代测序面板可能是不够的确定治疗方案的全谱精密肿瘤学。提供了一个更全面,但更昂贵,的选择。当实现这种类型的测试。分析大量的转移活检,奥地利奥和他的同事们现在发现相对有限的基因组进化的时候比较全基因组的活检之前和之后的护理标准治疗。

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来源
《Nature cancer.》 |2021年第12期|1290-1290|共1页
作者
Julia Simundza;
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正文语种英语
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metastasis; cancer therapy; Analyses, SequenceSequencingBiopsyMACHINE SHOP PRACTICEBiological MarkersSufficient;

机译：转移,癌症治疗,分析,SequenceSequencingBiopsyMACHINE商店PRACTICEBiological MarkersSufficient;

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Fitting whole-genome sequencing analysis for metastasis

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