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Production of (117m)Sn with high specific activity by cyclotron.

机译:回旋加速器生产高比活度的(117m)Sn。

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摘要

A method to produce (117m)Sn radionuclide using accelerator production route is described. A new method is proposed to separate the (117m)Sn. Specific activities and thick target yield for (116)Cd(alpha,3n)(117m)Sn reaction at E(alpha)=35MeV bombarding energy were determined. The estimated production yield of (117m)Sn was 37.5kBq/muAh for 13.16 mg/cm(2) natural cadmium-oxide target and 410 kBq/muAh for 11.07 mg/cm(2) highly enriched (95%) (116)CdO target. The method developed for separation of (117m)Sn from Cd using anion-exchange resin (Dowex -1x8, fluorine form, 400 mesh) can achieve 98% radiochemical yield of (117m)Sn with more than 99% radionuclidic purity. The estimated specific activity is 2.4 GBq/mg that can be reached with the used irradiation conditions.
机译:描述了一种使用促进剂生产路线生产(117m)Sn放射性核素的方法。提出了一种分离(117m)Sn的新方法。确定了在Eα= 35MeV轰击能下(116)Cdα(3n)(117m)Sn反应的比活和较厚的目标产率。 (117m)Sn的估计产量为13.16 mg / cm(2)天然氧化镉靶标为37.5kBq / muAh,对于11.07 mg / cm(2)的高浓缩(95%)(116)CdO为410 kBq / muAh目标。使用阴离子交换树脂(Dowex -1x8,氟形式,400目)从镉中分离出(117m)Sn的方法可以实现(117m)Sn的98%放射化学收率,放射性核素纯度超过99%。估计的比活度为2.4 GBq / mg,可在使用的辐照条件下达到。

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