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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >The VANILLA sensor as a beam monitoring device for X-ray radiation therapy
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The VANILLA sensor as a beam monitoring device for X-ray radiation therapy

机译：VANILLA传感器作为X射线放射治疗的光束监测设备

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Cancer treatments such as intensity-modulated radiotherapy (IMRT) require increasingly complex methods to verify the accuracy and precision of the treatment delivery. In vivo dosimetry based on measurements made in an electronic portal imaging device (EPID) has been demonstrated. The distorting effect of the patient anatomy on the beam intensity means it is difficult to separate changes in patient anatomy from changes in the beam intensity profile. Alternatively, upstream detectors scatter and attenuate the beam, changing the energy spectrum of the beam, and generate contaminant radiation such as electrons. We used the VANILLA device, a Monolithic Active Pixel Sensor (MAPS), to measure the 2D beam profile of a 6 MV X-ray beam at Bristol Hospital in real-time in an upstream position to the patient without clinically significant disturbance of the beam (0.1% attenuation). MAPSs can be made very thin (- 20 murn) with still a very good signal-to-noise performance. The VANILLA can reconstruct the collimated beam edge with approximately 64 mum precision.
机译：诸如调强放疗（IMRT）之类的癌症治疗需要越来越复杂的方法来验证治疗方法的准确性和精确性。已经证明了基于在电子门禁成像设备（EPID）中进行的测量的体内剂量测定法。患者解剖结构对束强度的扭曲作用意味着很难将患者解剖结构的变化与束强度分布的变化区分开。或者，上游检测器会散射和衰减光束，从而改变光束的能谱，并产生污染物辐射，例如电子。我们使用VANILLA设备（单片有源像素传感器（MAPS））在布里斯托尔医院实时测量患者上游位置的6 MV X射线束的2D束轮廓，而没有临床上明显的束流干扰（0.1％衰减）。 MAPS可以做得很薄（约20微米），但信噪比仍然很高。 VANILLA可以约64微米的精度重建准直光束的边缘。

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