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Assessment of intake and internal dose from iodine-131 for exposed workers handling radiopharmaceutical products

机译:评估处理放射性药物产品的暴露工人的碘131的摄入量和内部剂量

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摘要

Two methods for determination of internal dose due to 131I intake during the preparation and handling of iodine radiopharmaceutical products have been compared. The first method was based on the measurement of 131I in 24-hour urine samples while the second method was based on the measurement in vivo of 131I in thyroid. The results have shown that urine analysis method can be used as a screening test but not for internal dose assessment of exposed workers. Thyroid monitoring method was found to be more reliable and accurate method for assessing internal dose from 131I intake. In addition, the assessed internal dose showed that the annual internal effective dose for some workers was below 1mSv with no risk classification, whereas the results of other group of workers were between 1 and 6mSv with low risk classification. Only one worker reached 7.66mSv with high risk classification; and this worker must be monitored individually.
机译:比较了两种在碘放射性药物产品的制备和处理过程中确定因摄入131I而引起的内部剂量的方法。第一种方法基于24小时尿液样本中131I的测量,而第二种方法基于体内甲状腺中131I的测量。结果表明,尿液分析方法可以用作筛查测试,但不能用于暴露工人的内部剂量评估。甲状腺监测方法被认为是评估131I摄入量内部剂量的更可靠,更准确的方法。此外,评估的内部剂量表明,某些工人的年度内部有效剂量低于1mSv,没有风险分类,而其他一组工人的结果在1至6mSv之间,低风险分类。只有一名工人达到了7.66mSv的高风险分类;并且必须对该工人进行单独监视。

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