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Assessment of health risks from aflatoxins in rice commercialised in Riyadh, Kingdom of Saudi Arabia

机译:健康风险评估在大米中黄曲霉毒素商业化在利雅得,沙特阿拉伯王国

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摘要

This study aimed to assess the occurrence and health risk of aflatoxins (AF) in rice imported to Riyadh, Kingdom of Saudi Arabia (KSA). Rice samples (n=41) including long grain white rice (LGW), short grain white rice (SGW) and long grain yellow rice (LGY) were analysed using high performance liquid chromatography with fluorescence detection. Accordingly, the hepatocellular carcinoma (HCC) risk for the total population was estimated with regard to individuals positive for the hepatitis B virus surface antigen (HBsAg+) and HBsAg-negative individuals. The results of this study indicated that 68% of the samples were contaminated with an average AF concentration of 1.45 +/- 1.57 mu g/kg. The SGW had the highest value of contamination (mean=2.34 mu g/kg) followed by the LGY (1.36 mu g/kg) and the LGW (0.59 mu g/kg). The AF levels in all analysed samples were found to be below the prescribed limit of the KSA regulation (20 mu g/kg), and 1 sample (2.4%) had total AF level higher than European Commission limit (4 mu g/kg). However, estimation of the chronic effects revealed that the HCC risk was found 0.04 for HBsAg-and 1.04 for HBsAg+ per 105 individuals per year. The margin of exposure was found to be 72 for total AF. The results indicate that consumption of AF contaminated rice imported into Riyadh (KSA) may have public health consequences including risk of HCC, although levels are below the prescribed limit in the kingdom of Saudi Arabia as well as in European Union. This is the first study to investigate the occurrence of AF, and the related health risks, in rice imported to KSA.
机译:本研究旨在评估发生和健康风险的黄曲霉毒素(AF)大米进口利雅得,沙特阿拉伯王国(KSA)。样品(n = 41)包括长粒大米(LGW数据),细粒白米(信令转换)和长粮食黄米饭(LGY)分析了使用高液相色谱与荧光检测。肝细胞癌(HCC)的总风险人口估计有关人乙型肝炎病毒阳性表面抗原(HBsAg +)和HBsAg-negative个人。, 68%的样品被污染的房颤的平均浓度1.45 + / - 1.57亩克/公斤。污染(意味着= 2.34μg / kg)紧随其后LGY(1.36μg / kg)和LGW数据(0.59μg / kg)。房颤水平在所有分析样本被发现籍低于规定的限制监管(20μg / kg),和1示例(2.4%)房颤总水平高于欧洲委员会限制(4μg / kg)。慢性影响显示肝细胞癌的风险发现0.04 1.04 HBsAg-and HBsAg +每105人个人每年。发现72年总房颤。结果表明食用被污染的AF大米进口到利雅得(KSA)公共卫生后果包括肝细胞癌的风险,虽然水平低于规定的限制的沙特阿拉伯王国以及在欧洲联盟。房颤的发生,相关的健康风险,在大米进口到哪些国家。

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