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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Moderated Cf-252 neutron energy spectra in brain tissue and calculated boron neutron capture dose
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Moderated Cf-252 neutron energy spectra in brain tissue and calculated boron neutron capture dose

机译：脑组织中的Cf-252中子能谱适度和硼中子俘获剂量的计算

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摘要

While there is significant clinical experience using both low- and high-dose Cf-252 brachytherapy, combination therapy using B-10 for neutron capture therapy-enhanced Cf-252 brachytherapy has not been performed. Monte Carlo calculations were performed in a brain phantom (ICRU 44 brain tissue) to evaluate the dose enhancement predicted for a range of B-10 concentrations over a range of distances from a clinical Cf-252 source. These results were compared to experimental measurements and calculations published in the literature. For B-10 concentrations less than or equal to 50 mug/g, the B-10 neutron capture dose enhancement was small in comparison to the Cf-252 fast neutron dose. (C) 2004 Elsevier Ltd. All rights reserved.
机译：尽管有使用低剂量和大剂量Cf-252近距离放射治疗的丰富临床经验，但尚未进行使用B-10进行中子俘获疗法增强的Cf-252近距离放射治疗的联合治疗。在脑模型（ICRU 44脑组织）中进行了蒙特卡洛计算，以评估在距临床Cf-252来源一定距离范围内，针对一系列B-10浓度预测的剂量增加。将这些结果与文献中发表的实验测量结果和计算结果进行了比较。对于B-10浓度小于或等于50杯/克，与Cf-252快速中子剂量相比，B-10中子俘获剂量的增加很小。 （C）2004 Elsevier Ltd.保留所有权利。

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