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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Monte Carlo simulation of neutron irradiation facility developed for accelerator based in vivo neutron activation measurements in human hand bones
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Monte Carlo simulation of neutron irradiation facility developed for accelerator based in vivo neutron activation measurements in human hand bones

机译：中子辐照设备的蒙特卡罗模拟，用于基于加速器的人手骨骼体内中子活化测量

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摘要

The neutron irradiation facility developed at the McMaster University 3 MV Van de Graaff accelerator was employed to assess in vivo elemental content of aluminum and manganese in human hands. These measurements were carried out to monitor the long-term exposure of these potentially toxic trace elements through hand bone levels. The dose equivalent delivered to a patient during irradiation procedure is the limiting factor for IVNAA measurements. This article describes a method to estimate the average radiation dose equivalent delivered to the patient's hand during irradiation. The computational method described in this work augments the dose measurements carried out earlier [Arnold et al., 2002. Med. Phys. 29(11), 2718-2724]. This method employs the Monte Carlo simulation of hand irradiation facility using MCNP4B. Based on the estimated dose equivalents received by the patient hand, the proposed irradiation procedure for the IVNAA measurement of manganese in human hands [Arnold et al., 2002. Med. Phys. 29(11), 2718-2724] with normal (1 ppm) and elevated manganese content can be carried out with a reasonably low dose of 31 mSv to the hand. Sixty-three percent of the total dose equivalent is delivered by non-useful fast group (> 10 keV); the filtration of this neutron group from the beam will further decrease the dose equivalent to the patient's hand. (c) 2005 Elsevier Ltd. All rights reserved.
机译：麦克马斯特大学3 MV Van de Graaff加速器开发的中子辐照设备用于评估人体手中铝和锰的体内元素含量。进行这些测量是为了通过手骨水平监测这些潜在有毒微量元素的长期暴露。辐照过程中输送给患者的剂量当量是IVNAA测量的限制因素。本文介绍了一种估算辐照期间传递到患者手部的平均放射剂量当量的方法。在这项工作中描述的计算方法扩大了先前进行的剂量测量[Arnold等，2002。Med。物理29（11），2718-2724]。该方法采用了使用MCNP4B的手部照射设备的蒙特卡罗模拟。基于患者手收到的估计剂量当量，建议的用于IVNAA测量人手中锰的辐照程序[Arnold et al。，2002. Med。物理[29（11），2718-2724]具有正常（1 ppm）和较高的锰含量，可以以31 mSv的合理低剂量施于手。无用快速组（> 10 keV）输送了总剂量当量的63％;该中子群从射束中的过滤将进一步降低相当于患者手部的剂量。 （c）2005 Elsevier Ltd.保留所有权利。

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