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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Remote control production of an aqueous solution of no-carrier-added 34mCl- via the 32S(alpha,pn) nuclear reaction.
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Remote control production of an aqueous solution of no-carrier-added 34mCl- via the 32S(alpha,pn) nuclear reaction.

机译:通过32S(α,pn)核反应远程控制无载体添加的34mCl-水溶液的生产。

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摘要

A remote system was established for the production of a biologically important radionuclide, chlorine-34m (32.0min, beta(+) 53%, IT 47%). The (32)S(alpha,pn)(34m)Cl reaction on elemental sulfur of natural isotopic composition was adopted for the production method. The target sulfur was melted by heating in the target chamber and then irradiated with 65MeV alpha particles (58.2MeV on target) at 3 microA for 30min. Generated (34m)Cl was extracted remotely with hot water from the molten sulfur in the target chamber. Within 20min, [(34m)Cl]chloride was obtained as a 10+/-3mL aqueous solution at a yield of 450 +/- 90 MBq, which corresponds to a recovery efficiency of 79 +/- 17% (n = 5). Both radionuclidic and radiochemical purities were more than 99% with a specific activity of 1.1GBq/ micromol. Non-radioactive impurities in the solution were identified as F(-), Cl(-), NO(3)(-), SO(4)(2-); other unknown ions were also present.
机译:建立了一个远程系统,用于生产生物学上重要的放射性核素氯34m(32.0分钟,β(+)53%,IT 47%)。生产方法采用对天然同位素组成的元素硫进行(32)S(α,pn)(34m)Cl反应。通过在靶室中加热将靶硫熔化,然后在3 microA上用65MeVα粒子(靶上58.2MeV)辐照30分钟。用热水从目标室中的熔融硫中远程提取生成的(34m)Cl。在20分钟内,以10 +/- 3mL的水溶液形式获得[(34m)Cl]氯化物,收率450 +/- 90 MBq,对应于79 +/- 17%的回收率(n = 5) 。放射性核素和放射化学纯度均超过99%,比活为1.1GBq / micromol。溶液中的非放射性杂质被鉴定为F(-),Cl(-),NO(3)(-),SO(4)(2-);还存在其他未知离子。

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