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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Imaging and dosimetry of 99mTc EC annexin V: preliminary clinical study targeting apoptosis in breast tumors.
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Imaging and dosimetry of 99mTc EC annexin V: preliminary clinical study targeting apoptosis in breast tumors.

机译：99mTc EC Annexin V的影像学和剂量测定：针对乳腺癌肿瘤细胞凋亡的初步临床研究。

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摘要

BACKGROUND: Early detection of cellular events is important to predict the outcome of the patients. This study was aimed to use (99m)Tc EC-annexin V to image tumor cells undergoing apoptosis. METHODS: In 10 patients with breast cancer, scintigraphic images and dosimetric estimates were obtained after administering (99m)Tc EC-annexin V. RESULTS: Nine of the 10 cases showed detectable (99m)Tc EC-annexin V uptake in tumor. Higher values of T/N ratios are associated with patient after treatment. CONCLUSIONS: Apoptosis can be quantified using (99m)Tc EC-annexin V.
机译：背景：细胞事件的早期检测对于预测患者的预后至关重要。这项研究旨在使用（99m）Tc EC-annexin V对经历凋亡的肿瘤细胞成像。方法：在10例乳腺癌患者中，给予（99m）Tc EC-annexin V后可得到闪烁体图像和剂量学估计值。结果：10例病例中有9例可检测到（99m）Tc EC-annexinV。 T / N比值较高与患者治疗后相关。结论：可以使用（99m）Tc EC-annexin V来量化细胞凋亡。

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