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首页> 外文期刊>Neuro-oncology practice. >Long-term incidence of glioma in Olmsted County, Minnesota, and disparities in postglioma survival rate: a population-based study
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Long-term incidence of glioma in Olmsted County, Minnesota, and disparities in postglioma survival rate: a population-based study

机译：长期的神经胶质瘤发病率奥姆斯特德县,明尼苏达州,postglioma生存之间的差距率:以人群为基础的研究

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Background. We assessed glioma incidence and disparities in postglioma survival rate in the Olmsted County, Minnesota, population.Methods. This population-based study assessed the incidence of pathologically confirmed primary gliomas between January 1, 1995, and December 31, 2014. Age- and sex-adjusted incidence rates per 100 000 person-years were calculated and standardized to the US white 2010 population. We compared incidence trends of glioma during our study period with previously published Olmsted County data from 1950 to 1990. We assessed postglioma survival rates among individuals with different socioeconomic status (SES), which was measured by a validated individual HOUsing-based SES index (HOUSES).Results. We identified 135 incident glioma cases (93% white) with 20 pediatric (50% female) and 115 adult cases (44% female). Overall incidence rate during our study period, 5.51 per 100 000 person-years (95% Cl: 4.56-6.46), showed no significant changes and was similar to that seen in 1950 to 1990, 5.5 per 100 000 person-years.The incidence of pediatric (age < 20 years) glioma was 2.49 (95% Cl: 1.40-3.58), whereas adult glioma incidence was 6.47 (95% Cl: 5.26-7.67). Among those with grade II to IV gliomas, individuals with lower SES (< median HOUSES) had significantly lower 5-year survival rates compared to those with higher SES, adjusted hazard ratio 1.61 (95% Cl: 1.01-2.85).Conclusion. In a well-defined North American population, long-term glioma incidence appears stable since 1950. Significant socioeconomic disparities exist for postglioma survival.
机译：背景。postglioma存活率的之间的差距奥姆斯特德县、明尼苏达、population.Methods。以人群为基础的研究评估了主要病理证实神经胶质瘤之间的1995年1月1日,12月31日2014. 100 000人年计算标准化对美国白人2010人口。而在我们的神经胶质瘤的发病趋势与先前研究期间发表奥姆斯特德县从1950年到1990年的数据。postglioma个体的存活率不同的社会经济地位(SES)衡量一个人HOUsing-based进行验证.Results SES指数(房子)。神经胶质瘤发病病例(93%的白人)20儿科女性(50%)和115例成人病例(44%女性)。期间,每100 000人年(95% Cl: 5.514.56 - -6.46),显示无显著变化,类似于1950年到1990年,每100人5.5000人每年。< 20年)神经胶质瘤是2.49 (95% Cl: 1.40 - -3.58),而成人神经胶质瘤发病率是6.47 (95% Cl:5.26 - -7.67)。神经胶质瘤,个人SES较低(<值房屋)显著降低5年生存较高的利率相比SES,调整风险比为1.61 (95% Cl: 1.01 - -2.85) .Conclusion。在一个良好定义的北美人口,长期神经胶质瘤发病率出现稳定1950. postglioma生存。

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