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Sexual Orientation and Substance Use Treatment Outcomes Across Five Clinical Trials of Contingency Management

机译：性取向和物质使用治疗在五个临床试验的结果应急管理

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摘要

Lesbian, gay, and bisexual (LGB) individuals have elevated rates of substance use disorders and present to treatment with more severe substance use problems. Despite this health disparity, recent reviews highlight the paucity of studies reporting sexual orientation in substance use research (e.g., Flentje, Bacca, & Cochran, 2015). Using data from 5 clinical trials of contingency management (CM). the current study investigated the impact of sexual orientation on 3 substance use outcomes: treatment retention, longest duration of abstinence, and percent negative samples submitted. Participants (N = 912; mean age = 36.6 years; 51.1% female; 45% African American, 42.2% Caucasian) were randomized to standard care in community-based intensive outpatient treatment (IOP) or the same plus CM. Patients identifying as LGB made up 10.6% of the sample. A significant proportion identified as bisexual (8.2% of the total sample). Regardless of sexual orientation, participants receiving CM achieved better treatment outcomes than those receiving KR alone. There were no statistically significant differences between LGB and heterosexual participants in their response to IOP in general. and CM specifically. across all 3 treatment outcomes (ps > .05). However, equivalence testing revealed that outcomes were not statistically equivalent for LGB and heterosexual participants. with the exception of percentage of negative samples. which was equivalent within the CM group only. Differences in treatment response to CM and standard community-based IOP do not reach the level of statistical significance; however, in mast cases, we cannot conclude that treatment response is equivalent for LGB and heterosexual individuals.
机译：女同性恋、男同性恋、双性恋(激光)人物质使用障碍和升高目前治疗更严重的物质使用问题。最近的评论强调研究的不足报告在物质使用的性取向研究(如Flentje,浆果,科克伦,2015)。使用应急的5个临床试验的数据管理(CM)。3日的影响性取向的物质结果:治疗保留,最长禁欲时间,消极的百分比提交样品。= 36.6岁;美国人,42.2%的白人)被随机分配标准治疗在以社区为基础的强化门诊治疗(IOP)或者同一+厘米。病人识别的同性恋者占10.6%样本。双性恋(样本总数的8.2%)。的性取向,参与者接受厘米达到更好的治疗结果接收KR。性恋之间的显著差异异性恋的参与者在他们的反应眼压。治疗结果(p > . 05)。等价测试显示结果不是同性恋者和统计等效异性恋的参与者。比例的负样本。只相当于在CM组。CM和标准治疗反应以社区为基础的眼压不能达到的水平统计学意义;我们不能得出这样的结论:治疗反应等效为同性恋者和异性恋者的个人。

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