...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Applied Spectroscopy: Society for Applied Spectroscopy >A Noninvasive Method for Assessing Interior Skin Damage Caused by Chronological Aging and Photoaging Based on Near-Infrared Diffuse Reflection Spectroscopy
【24h】

A Noninvasive Method for Assessing Interior Skin Damage Caused by Chronological Aging and Photoaging Based on Near-Infrared Diffuse Reflection Spectroscopy

机译：基于近红外漫反射光谱的无创方法评估按时间顺序老化和光老化引起的内部皮肤损伤

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This paper reports a noninvasive method for evaluating skin aging based on near-infrared diffuse reflectance (NIR-DR) spectroscopy. Skin aging can be attributed to photoaging and chronological aging. Both types of aging are heavily involved in the skin changes that occur as we get older, for example, wrinkles or sagging skin. Our goal is to develop a noninvasive way to assess changes taking place inside the skin for each type of aging by using NIR-DR spectroscopy. Interior skin damages caused by photoaging and chronological aging were studied for an ultraviolet-B (UVB)-irradiated hairless mouse group (24 mice) and a non-irradiated group (29 mice) by using NIR-DR spectroscopy and principal component analysis (PCA). The results suggested the possibility of monitoring the contribution and the quantitative assessment of both types of aging taking place inside the skin by using the 5990-5490 cm~(-1) and 5000-4480 cm~(-1) regions of NIR-DR spectra. For the photoaging, structural changes in proteins are most clearly reflected by a shift of the band near 4880 cm~(-1) due to a combination of amide A and amide II modes. On the other hand, the chronological aging is associated with a change in collagen quantity as is seen in the intensity changes in NIR bands assigned to collagen. NIR-DR spectroscopy and PCA may allow us to noninvasively assess the degree of photoaging and chronological aging as the degeneration of elasticity in collagen protein and the degradation of protein quantity, respectively.
机译：本文报道了一种基于近红外漫反射光谱（NIR-DR）的非侵入性皮肤老化评估方法。皮肤老化可归因于光老化和按时间顺序的老化。两种类型的衰老都与随着年龄的增长而发生的皮肤变化密切相关，例如皱纹或皮肤松弛。我们的目标是开发一种无创方法，通过使用NIR-DR光谱仪评估每种衰老类型在皮肤内部发生的变化。使用NIR-DR光谱和主成分分析（PCA）研究了紫外线（B）照射的无毛小鼠组（24小鼠）和未照射的组（29小鼠）由光老化和按时间顺序老化引起的内部皮肤损伤。 ）。结果表明，通过使用NIR-DR的5990-5490 cm〜（-1）和5000-4480 cm〜（-1）区域，可以监测皮肤内部两种衰老的贡献并进行定量评估。光谱。对于光老化，由于酰胺A和酰胺II模式的结合，蛋白质的结构变化最明显地通过在4880cm-1（-1）附近的带的移动来反映。另一方面，如分配给胶原的NIR谱带的强度变化所见，按时间顺序的老化与胶原量的变化有关。 NIR-DR光谱学和PCA可能使我们能够无创地评估光老化和按时间顺序老化的程度，这分别是胶原蛋白的弹性下降和蛋白数量的下降。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号