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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Hemangiopericytoma/Solitary fibrous tumor of the oral cavity.
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Hemangiopericytoma/Solitary fibrous tumor of the oral cavity.

机译:血管内皮细胞瘤/口腔孤立性纤维瘤。

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摘要

Hemangiopericytoma/solitary fibrous tumor is a very rare tumor of uncertain malignant potential. About 300 such cases have been reported since 1942, when Stout and Murray described these tumors as "vascular tumors arising from Zimmerman's pericytes". Under the World Health Organization (WHO) classification, hemangiopericytomas and solitary fibrous tumors of the soft tissues are regarded as features of the same entity in the soft tissue fascicle. We report the case of a 54-year-old woman who presented with a painless right-side cheek mass of 2 cm maximum diameter. The lesion was completely removed by wide surgical resection. Histologically, the tumour had staghorn-like vasculature and immunohistochemistry for Calponin, CD68 KP1, AE1-AE3, smooth muscle actin and P63, S-100 was negative; that for CD34 was positive. A diagnosis of hemangiopericytoma/solitary fibrous tumor was rendered. The patient had a normal postoperative course of healing, and 24 months later remains asymptomatic, without signs of recurrence or metastasis. Because of the rarity and unpredictable biological behavior of these tumors, long-term follow-up is necessary even after radical resection because recurrence or development of metastasis may be delayed by many years.
机译:血管周细胞瘤/孤立性纤维瘤是恶性潜能不确定的非常罕见的肿瘤。自1942年以来,据报道,大约有300例此类病例,当时Stout和Murray将这些肿瘤描述为“ Zimmerman周细胞引起的血管肿瘤”。在世界卫生组织(WHO)的分类下,软组织的血管周细胞瘤和孤立性纤维瘤被视为软组织束中同一实体的特征。我们报道了一名54岁女性,其最大直径为2 cm的右侧颊颊肿块无痛。通过广泛的手术切除将病变完全清除。从组织学上看,该肿瘤具有鹿角状脉管系统和钙蛋白的免疫组织化学,CD68 KP1,AE1-AE3,平滑肌肌动蛋白和P63,S-100为阴性。 CD34阳性。诊断为血管周细胞瘤/孤立性纤维瘤。该患者术后恢复正常,24个月后仍无症状,无复发或转移迹象。由于这些肿瘤的稀有性和不可预测的生物学行为,即使在根治性切除后也需要长期随访,因为转移的复发或发展可能会延迟很多年。

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