Notes of a protein crystallographer: the molecular structure of evolutionary theory

Cele Abad-Zapatero

首页> 外文期刊>Acta crystallographica.Section D. Biological crystallography >Notes of a protein crystallographer: the molecular structure of evolutionary theory

【24h】

Notes of a protein crystallographer: the molecular structure of evolutionary theory

机译：笔记的蛋白质晶体:分子结构的进化理论

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

By the nature of our profession, macromolecular crystallographers study and analyze the structures of the molecular components of life in the utmost atomic detail. They expend a considerable amount of time expressing those delicate entities in bacterial or cell systems, purifying them, crystallizing them and, of course, solving their three-dimensional structures in their endless search for understanding the connection between their structure and their function in permitting the processes necessary for life. They seek the variants that can be crystallized and frozen in time and space to be able to unravel their three-dimensional structure. We do know what evolution is - or rather, how evolution operates - as we apply the forces of human selection into our expression systems to select the constructs, molecules and mutants of our interest for structural studies.

机译：我们的职业的本质,大分子晶体学家们研究和分析分子结构组件的生活最大的原子的细节。大量的时间表达精致的实体在细菌或细胞系统中,净化、结晶,当然,解决三维结构在他们没完没了的寻找了解他们之间的联系在允许的结构及其功能过程所必需的生活。变异可以结晶和冷冻能解开他们的时间和空间三维结构。进化是——或者说,进化如何运作——我们人类选择的力量我们的表达系统选择结构,分子和我们兴趣的突变体结构的研究。

著录项

来源
《Acta crystallographica.Section D. Biological crystallography》 |2009年第12期|1341-1349|共9页
作者
Cele Abad-Zapatero;
展开▼
作者单位

Center for Pharmaceutical Biotechnology, University of Illinois at Chicago, 900 So. Ashland St;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类化学;
关键词
Theory of Evolution; Mutants; component lifeSTRUCTURAL STUDYProteinvariantsNote Takingmolecular structurethree-dimentional structure;

机译：进化论;突变;组件lifeSTRUCTURAL STUDYProteinvariantsNoteTakingmolecular structurethree-dimentional结构;

相似文献

外文文献
中文文献

1. Analyzing Industrial Structure Evolution of Old Industrial Cities Using Evolutionary Resilience Theory:A Case Study in Shenyang of China [J] . GUAN Haoming, LIU Wenxin, ZHANG Pingyu, 中国地理科学（英文版） . 2018,第003期
2. Comment on ‘Note on X(3872) production at hadron colliders and its molecular structure' [J] . A.Esposito, B.Grinstein, L.Maiani, 中国物理C（英文版） . 2018,第011期
3. Note on X(3872) production at hadron colliders and its molecular structure [J] . Miguel Albaladejo, Feng-Kun Guo, Christoph Hanhart, 中国物理C（英文版） . 2017,第012期
4. 应用项目反应理论对友谊质量量表修定—以结构方程模型、层面理论多种技术支持修定量表的质量 Modifying Friendship Quality Questionnaire with Item Response Theory Approach——Validating with Facet Theory and Structure Equation Techniques [J] . Advances in Psychology . 2011,第1期

机译：应用项目反应理论对友谊质量量表修定—以结构方程模型、层面理论多种技术支持修定量表的质量 Modifying Friendship Quality Questionnaire with Item Response Theory Approach——Validating with Facet Theory and Structure Equation Techniques
5. Multi-objective design of synthetic biological circuits * * This publication is supported by the Swiss National Science Foundation as part of the NCCR Molecular Systems Engineering. [J] . Claude Lormeau, Miko?aj Rybiński, J?rg Stelling IFAC PapersOnLine . 2017,第1期

机译：合成生物电路的多目标设计 * * 此出版物由瑞士国家科学基金会作为NCCR Molecular的一部分得到支持系统工程。
6. Erratum: Ab initio studies of some hydrogen-bonded complexes of fluoroform - Evidence for blue-shifted behaviour (Journal of Molecular Structure (2012) 1023 (163-169)) [J] . Ramasami P., Ford T.A. Journal of Molecular Structure . 2012,第Null期

机译：勘误：氟仿氢键结配合物的从头算研究-蓝移行为的证据（Journal of Molecular Structure（2012）1023（163-169））
7. Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2 [D] . Yu, Qinhong. 2019

机译：Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2
8. Predicting the protein-protein interactions using primary structures with predicted protein surface [O] . Syu Yu-Tang, Chang Darby, Lin Po-Chang 2010

机译：predicting the protein-protein interactions using primary structures with predicted protein surface

Notes of a protein crystallographer: the molecular structure of evolutionary theory

摘要

著录项

相似文献

相关主题

期刊订阅